Phosphoinositides I: Enzymes of Synthesis and Degradation

1. The Phosphatidylinositol 4-Kinases: Don’t Call it a Comeback
Shane Minogue, Mark G. Waugh

2. PIP Kinases from the Cell Membrane to the Nucleus
Mark Schramp, Andrew Hedman, Weimin Li, Xiaojun Tan, Richard Anderson

3. The Phospholipase C Isozymes and Their Regulation
Aurelie Gresset, John Sondek, T. Kendall Harden

4. Phosphoinositide 3-Kinases—A Historical Perspective
Alex Toker

5. PI3Ks—Drug Targets in Inflammation and Cancer
Matthias Wymann

6. Phosphoinositide 3-Kinases in Health and Disease
Alessandra Ghigo, Fulvio Morello, Alessia Perino, Emilio Hirsch

7. Phosphoinositide Phosphatases: Just as Important as the Kinases
Jennifer M. Dyson, Clare G. Fedele, Elizabeth M. Davies, Jelena Becanovic, Christina A. Mitchell

8. The PTEN and Myotubularin Phosphoinositide 3-Phosphatases: Linking Lipid Signalling to Human Disease
Nicholas R. Leslie, Elizabeth M. Davies, David A. Sheffield, Priyanka Tibarewal, Clare G. Fedele, Christina A. Mitchell

Keywords: Biomedicine, Biomedicine general, Neurosciences, Human Genetics, Molecular Medicine, Gene Function, Neurochemistry