Systems Biology in Biotech & Pharma

1. Introduction: Discovery and Development—New Facet of Industry, New Tools and Lead Optimization
Aleš Prokop, Seth Michelson

2. Discovery: Use of Systems Biology for Identifying Targets
Aleš Prokop, Seth Michelson

3. Integrative Systems Biology I—Biochemistry: Phase I Lead Discovery and Molecular Interactions
Aleš Prokop, Seth Michelson

4. Integrative Systems Biology II—Molecular Biology: Phase 2 Lead Discovery and In Silico Screening
Aleš Prokop, Seth Michelson

5. Discovery: Computational Systems Biology (CSB) in Health and Disease I
Aleš Prokop, Seth Michelson

6. Development: In Vivo Pharmacology—Systems Biology in Health and Disease II
Aleš Prokop, Seth Michelson

7. Development: Pharmacokinetics—Systems Biology in Health and Disease III
Aleš Prokop, Seth Michelson

8. Development: Multiscale CSB—Simulation Tools
Aleš Prokop, Seth Michelson

9. Development: Drug Formulation and Delivery
Aleš Prokop, Seth Michelson

10. Development: Preclinical Model Based Drug Development
Aleš Prokop, Seth Michelson

11. Systems Biology: Impact on Pharma and Biotech
Aleš Prokop, Seth Michelson

Keywords: Biomedicine, Biomedicine general, Biotechnology, Applied Microbiology, Pharmaceutical Sciences/Technology