Sarcopenia – Age-Related Muscle Wasting and Weakness

1. Overview of Sarcopenia
Gordon S. Lynch

2. Muscle Wasting in Cancer and Ageing: Cachexia Versus Sarcopenia
Josep M. Argilés, Sílvia Busquets, Marcel Orpi, Roberto Serpe, Francisco J. López-Soriano

3. Age-Related Remodeling of Neuromuscular Junctions
Carlos B. Mantilla, Gary C. Sieck

4. Aging-Related Changes Motor Unit Structure and Function
Alexander Cristea, David E. Vaillancourt, Lars Larsson

5. Age-Related Decline in Actomyosin Structure and Function
LaDora V. Thompson

6. Excitation-Contraction Coupling Regulation in Aging Skeletal Muscle
Osvaldo Delbono

7. Alterations in Mitochondria and Their Impact in Aging Skeletal Muscle
Russell T. Hepple

8. Skeletal Muscle Collagen: Age, Injury and Disease
Luc E. Gosselin

9. Nuclear Apoptosis and Sarcopenia
Stephen E. Alway, Parco M. Siu

10. Age-Related Changes in the Molecular Regulation of Skeletal Muscle Mass
Aaron P. Russell, Bertrand Lèger

11. Genetic Variation and Skeletal Muscle Traits: Implications for Sarcopenia
Stephen M. Roth

12. Proteomic and Biochemical Profiling of Aged Skeletal Muscle
Kathleen O’Connell, Philip Doran, Joan Gannon, Pamela Donoghue, Kay Ohlendieck

13. Exercise and Nutritional Interventions to Combat Age-Related Muscle Loss
René Koopman, Lex B. Verdijk, Luc J. C. Loon

14. Reactive Oxygen Species Generation and Skeletal Muscle Wasting – Implications for Sarcopenia
Anne McArdle, Malcolm J. Jackson

15. Exercise as a Countermeasure for Sarcopenia
Donato A. Rivas, Roger A. Fielding

16. Role of Contraction-Induced Injury in Age-Related Muscle Wasting and Weakness
John A. Faulkner, Christopher L. Mendias, Carol S. Davis, Susan V. Brooks

17. Role of IGF-1 in Age-Related Loss of Skeletal Muscle Mass and Function
Chris D. McMahon, Thea Shavlakadze, Miranda D. Grounds

18. Role of Myostatin in Skeletal Muscle Growth and Development: Implications for Sarcopenia
Craig McFarlane, Mridula Sharma, Ravi Kambadur

19. Role of β-Adrenergic Signalling in Skeletal Muscle Wasting: Implications for Sarcopenia
James G. Ryall, Gordon S. Lynch

Keywords: Biomedicine, Biomedicine general, Geriatrics/Gerontology, Cell Biology, Sports Medicine, Medicine/Public Health, general