Apoptosome

1. Physiological and Pathological Role of Apoptosis
Virve Cavallucci, Marcello D’Amelio

2. Apoptosome Structure and Regulation
Elisabetta Ferraro, Claudia Fuoco, Flavie Strappazzon, Francesco Cecconi

3. Chemical Regulation of the Apoptosome: New Alternative Treatments for Cancer
Kelvin Cain

4. Molecules That Bind a Central Protein Component of the Apoptosome, Apaf-1, and Modulate Its Activity
Laura Mondragón, Mar Orzáez, Anna Gortat, Monica Sancho, Angel Messeguer, María Jesús Vicent, Enrique Pérez-Payá

5. Regulation of Cell Death and Survival by RNA Interference – The Roles of miRNA and siRNA
Paul Lingor

6. Beneficial Role of Taurine Against Myocardial Apoptosis During Ischemic Injury
Takashi Ito, Stephen W. Schaffer, Junichi Azuma

7. BAG3 Protein: Role in Some Neoplastic Cell Types and Identification as a Candidate Target for Therapy
Maria Pascale, Alessandra Rosati, Michelina Festa, Anna Basile, Morena d’Avenia, Antonia Falco, Gaetano Torino, Maria Caterina Turco

8. Targeting Survivin in Cancer Therapy: Pre-clinical Studies
Marzia Pennati, Marco Folini, Nadia Zaffaroni

9. Hsp70 and Hsp27: Emerging Targets in Cancer Therapy
Anne Laure Rérole, Anne Laure Joly, Dominique Thuringer, Carmen Garrido

10. Role of the RNA-Binding Protein HuR in Apoptosis and Apoptosome Function
Yuki Kuwano, Imed-Eddine Gallouzi, Myriam Gorospe

11. Acetylcholinesterase as a Pharmacological Target in Cancer Research
Sang Eun Park, Young Hyun Yoo

12. Putative Role of HCA66, A New Apaf-1 Interacting Protein, in the Physiopathology of NF1 Microdeletion Syndrome Patients
Patricia Rigou, Audrey Faye, Jean-Luc Poyet

13. Cristae Remodeling and Mitochondrial Fragmentation: A Checkpoint for Cytochrome c Release and Apoptosis?
Luca Scorrano

14. Apoptosome Pharmacological Manipulation: From Current Developments in the Laboratory to Clinical Implications
Marcello D’Amelio, Francesco Cecconi

15. The Therapeutic Role of Taurine in Ischaemia-Reperfusion Injury
Ross Kingston

16. Targeting Survivin in Cancer Therapy: Clinical Considerations
Tetsuhiro Tsuruma, Hidekaz Kameshima, Yuji Iwayama, Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Sato, Koichi Hirata

Keywords: Biomedicine, Cancer Research, Oncology, Cell Biology, Pharmacology/Toxicology, Apoptosis