Recent Advances in Thrombosis and Hemostasis 2008

Part 1. Coagulation Mechanism

1. Structure and Functions of Fibrinogen and Fibrin
Michael W. Mosesson

2. Vitamin K Cycles and ?-Carboxylation of Coagulation Factors
Darrel W. Stafford, Christine M. Hebling

3. Synthesis and Secretion of Coagulation Factor VIII
Michael U. Callaghan, Randal J. Kaufman

4. Structure and Biological Function of Factor XI
Kazuo Fujikawa

5. Structural Insights into the Life History of Thrombin
James A. Huntington

6. A Molecular Model of the Human Prothrombinase Complex
Stephen J. Everse, Ty E. Adams, Kenneth G. Mann

7. Lipid Mediators and Tissue Factor Expression
Hiroyuki Takeya, Koji Suzuki

8. Tissue Factor Pathway Inhibitor: Structure and Function
Hisao Kato

9. Biology of an Antithrombotic Factor—ADAMTS13
Fumiaki Banno, Toshiyuki Miyata

10. Antithrombin and Heparin Cofactor II: Structure and Functions
Takehiko Koide

Part 2. Endothelial Cells and Inflammation

11. High-Mobility Group Box 1: Missing Link Between Thrombosis and Inflammation?
Takashi Ito, Ko-ichi Kawahara, Teruto Hashiguchi, Ikuro Maruyama

12. Coagulation, Inflammation, and Tissue Remodeling
Koji Suzuki, Tatsuya Hayashi, Osamu Taguchi, Esteban Gabazza

13. Structure and Function of the Endothelial Cell Protein C Receptor
Kenji Fukudome

14. New Aspects of Antiinflammatory Activity of Antithrombin: Molecular Mechanism(s) and Therapeutic Implications
Naoaki Harada, Kenji Okajima

Part 3. Platelets

15. Platelet Collagen Receptors
Stephanie M. Jung, Masaaki Moroi

16. Positive and Negative Regulation of Integrin Function
Yoshiaki Tomiyama, Masamichi Shiraga, Hirokazu Kashiwagi

17. GPIb-Related Signaling Pathways in Platelets
Yukio Ozaki

18. Sphingosine 1-Phosphate as a Platelet-Derived Bioactive Lipid
Yutaka Yatomi

19. Polymorphisms of Platelet Membrane Glycoproteins
Yumiko Matsubara, Mitsuru Murata, Yasuo Ikeda

20. Platelet Procoagulant Activity Appeared by Exposure of Platelets to Blood Flow Conditions
Shinya Goto

Part 4. Tissue Proteolysis

21. Regulation of Cellular uPA Activity and Its Implication in Pathogenesis of Diseases
Soichi Kojima

22. Role of tPA in the Neural System
Nobuo Nagai, Tetsumei Urano

23. Role of Fibrinolysis in the Nasal System
Takayuki Sejima, Yoichi Sakata

24. Role of Fibrinolysis in Hepatic Regeneration
Kiyotaka Okada, Shigeru Ueshima, Osamu Matsuo

25. Pathophysiology of Transglutaminases Including Factor FXIII
Akitada Ichinose

Part 5. Vascular Development and Regeneration

26. A Linkage in the Developmental Pathway of Vascular and Hematopoietic Cells
Jun K. Yamashita

27. Atherosclerosis and Angiogenesis: Double Face of Neovascularization in Atherosclerotic Intima and Collateral Vessels in Ischemic Organs
Katsuo Sueishi, Mitsuho Onimaru, Yutaka Nakashima

Part 6. Hemorrhagic Diathesis

28. Hemophilia A and Inhibitors
Midori Shima, Akira Yoshioka

29. von Willebrand Disease: Diagnosis and Treatment
Masato Nishino

Part 7. Other Topics of Thrombosis and Hemostasis

30. Age-Related Homeostasis and Hemostatic System
Kotoku Kurachi, Sumiko Kurachi, Toshiyuki Hamada, Emi Suenaga, Tatiana Bolotova, Elena Solovieva

31. Molecular Evolution of Blood Clotting Factors with Special Reference to Fibrinogen and von Willebrand Factor
Sadaaki Iwanaga, Soutaro Gokudan, Jun Mizuguchi

32. Snake Venoms and Other Toxic Components Affecting Thrombosis and Hemostasis
Yasuo Yamazaki, Takashi Morita

33. Structures and Potential Roles of Oligosaccharides in Human Coagulation Factors and von Willebrand Factor
Taei Matsui, Jiharu Hamako, Koiti Titani

Part 8. Clinicals: Thrombosis-related Disorders and Recent Topics

34. Hypercoagulable States
Tetsuhito Kojima, Hidehiko Saito

35. Etiopathology of the Antiphospholipid Syndrome
Tatsuya Atsumi, Olga Amengual, Takao Koike

36. Malignancy and Thrombosis
Hiroshi Kobayashi, Ryuji Kawaguchi, Yoriko Tsuji, Yoshihiko Yamada, Mariko Sakata, Seiji Kanayama, Shoji Haruta, Hidekazu Oi

37. Disseminated Intravascular Coagulation
Hideo Wada

38. Current Clinical Status of Venous Thromboembolism in Japan
Mashio Nakamura, Takeshi Nakano, Satoshi Ota, Norikazu Yamada, Masatoshi Miyahara, Naoki Isaka, Masaaki Ito

39. Platelet Activity and Antiplatelet Therapy in Patients with Ischemic Stroke and Transient Ischemic Attack
Shinichiro Uchiyama, Tomomi Nakamura, Yumi Kimura, Masako Yamazaki

40. Clinical Role of Recombinant Factor Vlla in Bleeding Disorders
Harold R. Roberts, Dougald M. Monroe, Nigel S. Key

41. Clinical Role of Protein S Deficiency in Asian Population
Naotaka Hamasaki, Taisuke Kanaji

42. Atherothrombosis and Thrombus Propagation
Atsushi Yamashita, Yujiro Asada

43. Thrombotic Microangiopathy
Yoshihiro Fujimura, Masanori Matsumoto, Hideo Yagi

Keywords: Medicine & Public Health, Internal Medicine, Hematology, Molecular Medicine, Cell Biology