Metallomics

Part I. Overview

1. Metallomics: Integrated Biometal Science
Hiroki Haraguchi

Part II. Analytical Techniques and Strategies Surrounding Metallomics

2. Speciation and Identification of Chalcogen-Containing Metabolites
Yasumitsu Ogra

3. Visualization of Intracellular Elements Using Scanning X-Ray Fluorescence Microscopy
Mari Shimura, Lukasz Szyrwiel, Satoshi Matsuyama, Kazuto Yamauchi

4. Quantitative Elemental Bioimaging Protocol Using Femtosecond-Laser Ablation-ICP-Mass Spectrometry Coupled with Glass Standard Reference Material
Yoshiki Makino, Seiya Ohara, Marina Yamada, Sho Mukoyama, Kentaro Hattori, Shuhei Sakata, Yuki Tanaka, Toshihiro Suzuki, Atsuko Shinohara, Takehisa Matsukawa, Kazuhito Yokoyama, Takafumi Hirata

5. Single Cell Analysis by Using ICP-MS
Shin-ichi Miyashita, Shin-ichiro Fujii, Kaori Shigeta, Kazumi Inagaki

6. Synchrotron Radiation X-Ray Analysis of Metal-Accumulating Plants
Akiko Hokura, Emiko Harada

7.
77Se NMR Spectroscopy for Speciation Analysis of Selenium Compounds
Noriyuki Suzuki, Yasumitsu Ogra

8. Protein Quantification and Quantitative Phosphorylation Analysis by the Determination of Hetero Atoms (S and P) by Means of nanoHPLC-ICPMS
Yoshinari Suzuki, Naoki Furuta

9. Analysis of Drug Active Pharmaceutical Ingredients and Biomolecules Using Triple Quadrupole ICP-MS
Naoki Sugiyama, Yasuyuki Shikamori

10. Highly Sensitive Analysis of Proteins and Metabolites by Metal Tagging Using LC-ICP-MS
Daigo Iwahata

Part III. Application of Metallomics in Molecular Biology, Medicine and Pharmaceutical Sciences

11. Comprehensive Element Analysis of Prokaryotic and Eukaryotic Cells as well as Organelles by ICP-MS
Tomonari Umemura, Yuichiro Matsui, Shinnosuke Sakagawa, Taku Fukai, Eiji Fujimori, Hidetoshi Kumata, Motohide Aoki

12. Iron Isotope Signature in Red Blood Cell Samples from Japanese Female Donors of Various Ages
Yu-ki Tanaka, Kohshiro Takata, Takahiro Kawasaki, Atsuko Shinohara, Kazuko Ishikawa-Takata, Takafumi Hirata

13. Roles of Zinc Transporters in Cellular Transport of Cadmium and Manganese
Seiichiro Himeno, Hitomi Fujishiro

14. Link Between Metal Homeostasis and Neurodegenerative Diseases: Crosstalk of Metals and Amyloidogenic Proteins at the Synapse
Dai Mizuno, Masahiro Kawahara

15. New Insight into Metallomics in Cognition
Atsushi Takeda, Hanuna Tamano

16. Frontier of Development for Metallodrugs on the Basis of Metallomic Pharmacology and Medicinal Inorganic Chemistry
Hiroyuki Yasui, Yutaka Yoshikawa

Keywords: Biomedicine, Human Physiology, Biochemistry, general, Analytical Chemistry