Group-Sequential Clinical Trials with Multiple Co-Objectives

1. Introduction
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

2. Interim Evaluation of Efficacy in Clinical Trials with Two Co-primary Endpoints
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

3. Sample Size Recalculation in Clinical Trials with Two Co-primary Endpoints
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

4. Interim Evaluation of Efficacy or Futility in Clinical Trials with Two Co-primary Endpoints
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

5. Interim Evaluation of Efficacy in Clinical Trials with Two Primary Endpoints
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

6. Group-Sequential Three-Arm Non-inferiority Clinical Trials
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

7. Future Developments
Toshimitsu Hamasaki, Koko Asakura, Scott R. Evans, Toshimitsu Ochiai

Keywords: Statistics, Statistical Theory and Methods, Statistics for Life Sciences, Medicine, Health Sciences, Statistics for Social Science, Behavorial Science, Education, Public Policy, and Law