Personalized Treatment of Breast Cancer

Part I. Treatment for the Patients Having Breast Cancer High-Risk

1. Risk-Reducing Surgery for Breast Cancer Patients with BRCA Mutations
Eun-Kyu Kim, Sung-Won Kim, Dong-Young Noh

2. Prophylactic Risk-Reducing Surgery for Breast Cancer
Mihir M. Shah, Holly J. Pederson, Risal Djohan, Joseph P. Crowe, Stephen R. Grobmyer

3. Merits and Demerits of Practice for Hereditary Breast and Ovarian Cancer Syndrome (Advices and Issues)
Hideko Yamauchi

Part II. Axillary Treatment

4. Sentinel Lymph Node Biopsy and Neoadjuvant Chemotherapy in Breast Cancer Patients
John R. Benson

5. Axillary Reverse Mapping (ARM) as a Means to Reduce Lymphedema During Sentinel Lymph Node or Axillary Node Dissection
V. Suzanne Klimberg, Michael Douek

6. Ultrasound for Axillary Staging
Chiun-Sheng Huang

7. One-Step Nucleic Acid Amplification (OSNA) Assay for Primary Breast Cancer
Seigo Nakamura, Katsutoshi Enokido

8. Management of the Clinically Node-Negative Axilla in Primary Breast Cancer
Abdul Q. Alarhayem, Ismail Jatoi

9. Lymphatic Mapping and Optimization of Sentinel Lymph Node Dissection
Tomoharu Sugie, Takashi Inamoto

Part III. Radiation Therapy

10. Personalisation of Radiotherapy for Breast Cancer
Ian H. Kunkler, Carol Ward, Corey Speers, Lori Pierce, Felix Feng, James Meehan, Simon P. Langdon

11. New Technologies in Radiation Therapy
Michio Yoshimura, Chikako Yamauchi

12. Radiotherapy Following Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer
Nisha Ohri, Alice Ho

Part IV. Preoperative Hormone Therapy

13. Novel Translational Research of Neo-adjuvant Endocrine Therapy
Alexey A. Larionov

14. Alterations of Biomarkers by Neoadjuvant Endocrine Therapy
Yukiko Shibahara, Hironobu Sasano

Part V. Preoperative Chemotherapy

15. Essence of Neoadjuvant Therapy
Jenny Furlanetto, Gunter Minckwitz

16. The Challenge to Overcome Triple-Negative Breast Cancer Heterogeneity
Hiroko Masuda, Norikazu Masuda

17. Surgical Management of Breast Cancer After Preoperative Systemic Treatment
John Mathew, Carol-Ann Courtney, Kelly K. Hunt, John F. Robertson

18. Imaging of Tumor Response by Preoperative Systemic Treatment
Shotaro Kanao, Masako Kataoka

Part VI. Preoperative Anti-HER2 Therapy

19. Human Epidermal Growth Factor Receptor (HER) Family Molecular Structure
Mark D. Pegram, Ralf Landgraf

20. Locoregional Therapy Following Neoadjuvant Therapy for HER-2+ Breast Cancer: Opportunities and Challenges
Stephen R. Grobmyer, Stephanie A. Valente, Sheen Cherian, Holly J. Pederson, Jame Abraham

Part VII. Mathematical Prediction/Assessment Model

21. Nomograms to Predict Positive Resection Margin and to Predict Three or More Positive Lymph Nodes
Eunshin Lee, Wonshik Han

22. Practical Use of Nomograms
José Luiz B. Bevilacqua, Paulo R. Alcantara Filho, Lillian Fraianella, Carla Curi

23. Data Mining and Mathematical Model Development
Masahiro Sugimoto, Masahiro Takada

Keywords: Medicine & Public Health, Surgical Oncology, Primary Care Medicine, Surgery