Cytokine Frontiers

Part I. Cytokines in Inflammatory Disorders

1. The Interleukin-1 Family
Charles A. Dinarello, Mihai G. Netea

2. IL-6 and Inflammatory Diseases
Daisuke Kamimura, Yasunobu Arima, Toshio Hirano, Hideki Ogura, Masaaki Murakami

3. The Roles of IL-17A and IL-17F in Infection and Inflammatory Disorders
Harumichi Ishigame, Susumu Nakae

4. IL-18
Wen Li, Yoshimasa Tanaka, Haruki Okamura

5. Interleukin-21: A Pleiotropic Mediator of Immunity and Inflammation with Broad Therapeutic Potential
Rosanne Spolski, Warren J. Leonard

6. Interleukin-22: A Bridge Between Epithelial Innate Host Defense and Immune Cells
Xiaoting Wang, Wenjun Ouyang

7. IL-23 in Health and Disease
Jonathan P. Sherlock, Luis A. Zuniga, Daniel J. Cua

8. IL-36: An Epithelial Cytokine Important in Psoriasis
John E. Sims, Solenne Vigne, Cem Gabay, Jennifer E. Towne

9. Anti-TNF Therapy: 20 Years from Our First Therapeutic Adventure
Jagdeep Nanchahal, Peter Taylor, Richard Williams, Marc Feldmann

Part II. Cytokines in Allergic Disorders

10. Interleukin-25: A Key Initiator of Type 2 Immune Responses
Hiroshi Nakajima, Tomohiro Tamachi, Koichi Hirose

11. Interleukin-33: A Multifunctional Alarmin that Promotes Both Health and Disease
Kazufumi Matsushita, Tomohiro Yoshimoto

12. Thymic Stromal Lymphopoietin (TSLP)
Steven F. Ziegler, Florence Roan, Bryan D. Bell, Thomas A. Stoklasek, Masayuki Kitajima, Hongwei Han

Part III. Cytokines in Immunological Tolerance and Anti-inflammation

13. Interleukin-10: Cytokines in Anti-inflammation and Tolerance
Ashleigh Howes, Philippa Stimpson, Paul Redford, Leona Gabrysova, Anne O’Garra

14. Interleukin-27: Regulation of Immune Responses and Disease Development by a Pleiotropic Cytokine with Pro- and Anti-inflammatory Properties
Izuru Mizoguchi, Kaname Higuchi, Kana Mitobe, Ren Tsunoda, Junichiro Mizuguchi, Takayuki Yoshimoto

15. Interleukin-35: A Novel Mediator of Peripheral Tolerance
Greg M. Delgoffe, Dario A. A. Vignali

Keywords: Biomedicine, Immunology, Cytokines and Growth Factors, Cell Biology