Chembiomolecular Science

1. Chemistry of Mycolactones, the Causative Toxins of Buruli Ulcer
Yoshito Kishi

2. Practical Synthesis of Tamiflu and Beyond
Motomu Kanai

3. An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis
Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai, Futoshi Hasegawa, Takeharu Nakashima, Nobuaki Matsumori, Michio Murata

4. Inhibitors of Fatty Acid Amide Hydrolase
Dale L. Boger

5. Small Molecule Tools for Cell Biology and Cell Therapy
Motonari Uesugi

6. Toward the Discovery of Small Molecules Affecting RNA Function
Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi, Asako Murata, Masaki Hagihara, Kazuhiko Nakatani

7. New Insights from a Focused Library Approach Aiming at Development of Inhibitors of Dual-Specificity Protein Phosphatases
Go Hirai, Ayako Tsuchiya, Mikiko Sodeoka

8. The Deep Oceans as a Source for New Treatments for Cancer
William Fenical, James J. Clair, Chambers C. Hughes, Paul R. Jensen, Susana P. Gaudêncio, John B. MacMillan

9. Search for New Medicinal Seeds from Marine Organisms
Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai

10. Identification of Protein–Small Molecule Interactions by Chemical Array
Hiroyuki Osada, Siro Simizu

11. Small Molecule-Induced Proximity
Fu-Sen Liang, Gerald R. Crabtree

12. High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing
Erik S. Anderson, Peter Stoilov, Robert Damoiseaux, Douglas L. Black

13. Identification of Signaling Pathways That Mediate Dietary Restriction-Induced Longevity in Caenorhabditis elegans

Masaharu Uno, Sakiko Honjoh, Eisuke Nishida

14. Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis
Miki Kamiyama, Takehiro Sato, Kohsuke Takeda, Hidenori Ichijo

15. Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal
Laura L. Kiessling

16. Cell-Surface Glycoconjugates Controlling Human T-Lymphocyte Homing: Implications for Bronchial Asthma and Atopic Dermatitis
Reiji Kannagi, Keiichiro Sakuma, Katsuyuki Ohmori

17. Establishment of a Novel System for Studying the Syk Function in B Cells
Tomohiro Kurosaki, Clifford A. Lowell

18. Visual Screening for the Natural Compounds That Affect the Formation of Nuclear Structures
Kaya Shigaki, Kazuaki Tokunaga, Yuki Mihara, Yota Matsuo, Yamato Kojimoto, Hiroaki Yagi, Masayuki Igarashi, Tokio Tani

19. Versatile Orphan Nuclear Receptor NR4A2 as a Promising Molecular Target for Multiple Sclerosis and Other Autoimmune Diseases
Shinji Oki, Benjamin J. E. Raveney, Yoshimitsu Doi, Takashi Yamamura

20. Antiviral MicroRNA
Ryota Ouda, Takashi Fujita

21. Synaptic Function Monitored Using Chemobiomolecular Indicators
Masamitsu Iino

22. Practical Catalytic Asymmetric Synthesis of a Promising Drug Candidate
Masakatsu Shibasaki

23. Hunting the Targets of Natural Product-Inspired Compounds
Slava Ziegler, Herbert Waldmann

24. Chemical Approaches for Understanding and Controlling Infectious Diseases
Hirokazu Arimoto

25. Nongenomic Mechanism-Mediated Renal Fibrosis-Decreasing Activity of a Series of PPAR-γ Agonists
Hiroyuki Miyachi

26. Novel Carbohydrate-Based Inhibitors That Target Influenza A Virus Sialidase
Mark Itzstein

27. Multidrug Efflux Pumps and Development of Therapeutic Strategies to Control Infectious Diseases
Kunihiko Nishino

28. Enzymes as Chemotherapeutic Agents
Ronald T. Raines

29. Mechanism of Action of New Antiinfectious Agents from Microorganisms
Nobuhiro Koyama, Hiroshi Tomoda

30. Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease
Yimin Hua, Kentaro Sahashi, Frank Rigo, Gene Hung, C. Frank Bennett, Adrian R. Krainer

31. Modulation of Pre-mRNA Splicing Patterns with Synthetic Chemicals and Their Clinical Applications
Masatoshi Hagiwara

Keywords: Life Sciences, Biochemistry, general, Cell Biology, Molecular Medicine