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Hirabayashi, Yoshio

Sphingolipid Biology

Hirabayashi, Yoshio - Sphingolipid Biology, ebook

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ISBN: 9784431342007
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Table of contents

Part 1. Overview

1. Sphingolipids Synthesis, Transport and Cellular Signaling
Yoshio Hirabayashi, Yasuyuki Igarashi, Alfred H. Merrill

Part 2. Biosynthesis, Transport of Sphingolipids

2. Serine Palmitoyltransferase
Jia Wei, Tokumbo Yerokun, Martina Liepelt, Amin Momin, Elaine Wang, Kentaro Hanada, Alfred H. Merrill

3. Ceramide Synthase
Irene Pankova-Kholmyansky, Anthony H. Futerman

4. Dihydroceramide: Sphinganine ?4-Desaturase and C4-Hydroxylase
Akemi Suzuki, Fumio Omae, Ayako Enomoto

5. Metabolizing Enzymes Such As Sphingomyelin Synthase Induce Cell Death by Increasing Ceramide Content
Toshiro Okazaki

6. Glucosylceramide and Galactosylceramide Synthase
James A. Shayman

7. Synthesis, Metabolism, and Trans-Bilayer Movement of Long-Chain Base
Akio Kihara, Yasuyuki Igarashi

8. Molecular Mechanism of Ceramide Trafficking from the Endoplasmic Reticulum to the Golgi Apparatus in Mammalian Cells
Kentaro Hanada, Miyuki Kawano, Keigo Kumagai

9. Sphingolipid Trafficking
Kouichi Funato, Howard Riezman

10. Current Perspectives on Saccharomyces cerevisiae Sphingolipids
Robert C. Dickson, Robert L. Lester

Part 3. Generation and Degradation of Sphingolipid Signaling Molecules

11. Generation of Signaling Molecules by De Novo Sphingolipid Synthesis
Kazuyuki Kitatani, L. Ashley Cowart, Yusuf A. Hannun

12. Overview of Acid and Neutral Sphingomyelinases in Cell Signaling
Youssef Zeidan, Norma Marchesini, Yusuf A. Hannun

13. Neutral Ceramidase as an Integral Modulator for the Generation of S1P and S1P-Mediated Signaling
Makoto Ito, Motohiro Tani, Yukihiro Yoshimura

14. Activation of Sphingosine Kinase 1
Michael Maceyka, Sergio E. Alvarez, Sheldon Milstien, Sarah Spiegel

15. Ceramide 1-Phosphate
Susumu Mitsutake, Tack-Joong Kim, Yasuyuki Igarashi

16. Sphingosine-1-Phosphate Lyase
Julie D. Saba

Part 4. Membrane Domain and Biological Function

17. Close Interrelationship of Sphingomyelinase and Caveolin in Triton X-100-lnsoluble Membrane Microdomains
Keiko Tamiya-Koizumi, Takashi Murate, Katsumi Tanaka, Yuji Nishizawa, Nobuhiro Morone, Jiro Usukura, Yoshio Hirabayashi

18. Roles of Membrane Domains in the Signaling Pathway for B Cell Survival
Miki Yokoyama, Tomoko Kimura, Sachio Tsuchida, Hiroaki Kaku, Kiyoshi Takatsu, Yoshio Hirabayashi, Masaki Yanagishita

19. The Role of Lipid Rafts in Axon Growth and Guidance
Hiroyuki Kamiguchi

20. Sphingolipids and Multidrug Resistance of Cancer Cells
Gerrit Meer, Maarten Egmond, David Halter

Part 5. Membrane Lipid Domain and Human Pathobiology

21. A New Pathological Feature of Insulin Resistance and Type 2 Diabetes: Involvement of Ganglioside GM3 and Membrane Microdomains
Jin-ichi Inokuchi, Kazuya Kabayama, Takashige Sato, Yasuyuki Igarashi

22. Neuronal Cell Death in Glycosphingolipidoses
Yaacov Kacher, Anthony H. Futerman

23. Endocytic Trafficking of Glycosphingolipids in Sphingolipidoses
Amit Choudhury, David L. Marks, Richard E. Pagano

24. Ganglioside and Alzheimer’s Disease
Katsuhiko Yanagisawa

25. Modulation of Proteolytic Processing by Glycosphingolipids Generates Amyloid ?-Peptide
Irfan Y. Tamboli, Kai Prager, Esther Barth, Micheal Heneka, Konrad Sandhoff, Jochen Walter

26. Hereditary Sensory Neuropathy
Simon J. Myers, Garth A. Nicholson

27. Ceramide, Ceramide Kinase and Vision Defects: A BLIND Spot for LIPIDS
Roser Gonzàlez-Duarte, Miquel Tuson, Gemma Marfany

28. Fumonisin Inhibition of Ceramide Synthase: A Possible Risk Factor for Human Neural Tube Defects
Ronald T. Riley, Kenneth A. Voss, Marcy Speer, Victoria L. Stevens, Janee Gelineau-van Waes

29. Sphingolipids and Cancer
Eva M. Schmelz, Holly Symolon

Part 6. S1P Signaling and SIPR

30. Sphingosine-1-Phosphate and the Regulation of Immune Cell Trafficking
Maria Laura Allende, Richard L. Proia

31. Sphingolipids and Lung Vascular Barrier Regulation
Liliana Moreno, Steven M. Dudek, Joe G. N. Garcia

32. Signaling Mechanisms for Positive and Negative Regulation of Cell Motility by Sphingosine-1-Phosphate Receptors
Yoh Takuwa, Naotoshi Sugimoto, Noriko Takuwa, Yasuyuki Igarashi

33. Sphingosine 1-Phosphate-Related Metabolism in the Blood Vessel
Yutaka Yatomi, Shinya Aoki, Yasuyuki Igarashi

Part 7. Advanced Technology in Sphingolipid Biology

34. Conventional/Conditional Knockout Mice
Ichiro Miyoshi, Tadashi Okamura, Noriyuki Kasai, Tetsuyuki Kitmoto, Shinichi Ichikawa, Soh Osuka, Yoshio Hirabayashi

35. Biosynthesis and Function of Drosophila Glycosphingolipids
Ayako Koganeya-Kohyama, Yoshio Hirabayashi

36. Characterization of Genes Conferring Resistance Against ISP-1/Myriocin-Induced Sphingolipid Depletion in Yeast
Hiromu Takematsu, Yasunori Kozutsumi

37. Lysenin: A New Probe for Sphingomyelin
Toshihide Kobayashi, Akiko Yamaji-Hasegawa

38. Structural Biology of Sphingolipid Synthesis
Hiroko Ikushiro, Akihiro Okamoto, Hideyuki Hayashi

39. A Computer Visualization Model for the De Novo Sphingolipid Biosynthetic Pathway
Jin Young Hong, Jeremy C. Allegood, Samuel Kelly, Elaine Wang, Alfred H. Merrill, May Dongmei Wang

Keywords: Life Sciences, Cell Biology, Biochemistry, general

Author(s)
 
 
Publisher
Springer
Publication year
2006
Language
en
Edition
1
Page amount
557 pages
Category
Natural Sciences
Format
Ebook
eISBN (PDF)
9784431342007

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