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Hoffmann, Reinhard W.

Classical Methods in Structure Elucidation of Natural Products

Hoffmann, Reinhard W. - Classical Methods in Structure Elucidation of Natural Products, ebook

126,50€

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ISBN: 9783906390789
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Organic chemistry as we know it today originated from a preoccupation with substances isolated from nature. In the period from 1860 to 1960, the main task was to elucidate their molecular structure by way of degradation and synthesis. In light of the limited experimental methods available and the lack of established reference compounds, this represented an unparalleled intellectual challenge.
This book makes use of twenty-five representative examples to retrace the great accomplishments made by the generation of chemists during this era. At the same time, it questions the reliability of the experimental results when judged by today's criteria, particularly since the structures for numerous natural products are stated as established facts in standard text books.
With each chapter devoted to one organic compound, the author combines results from historic experiments to trace a line of evidence that may follow the path put forward by the original contributors. However, in some cases the experimental facts have been combined to form another, hopefully shorter, line of evidence. As a result, readers are able to determine for themselves the 'facts behind the established structure assignments' of a number of important natural products.

Keywords: Analytical Chemistry, Pharmaceutical & Medicinal Chemistry, Analytical Chemistry, Pharmaceutical & Medicinal Chemistry

Author(s)
Publisher
John Wiley and Sons, Inc.
Publication year
2018
Language
en
Edition
1
Page amount
280 pages
Category
Natural Sciences
Format
Ebook
eISBN (ePUB)
9783906390789
Printed ISBN
9783906390734

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