The Grand Challenge for the Future

1. Economic aspects of vaccines and vaccination: a global perspective
Philippe P.A. Beutels

2. How and why vaccines are made
Stanley A. Plotkin, James M. Robinson

3. How can the industrial world help to implement new vaccines against poverty-related diseases?
Ole F. Olesen, Arnd Hoeveler

4. New approaches towards development, production and use of developing-country market vaccines in developing countries
Luis Jodar, John D. Clemens

5. Novel vaccination strategies
Maria Lattanzi, Rino Rappuoli

6. Design and selection of vaccine adjuvants: principles and practice
Carl R. Alving, Gary R. Matyas

7. Vaccination in the context of immunological immaturity
Ann M. Arvin, David B. Lewis

8. Regulatory issues in the development of new vaccines with a special emphasis on safety aspects
François Verdier

9. Clinical trials in developing countries: ethical issues
Veronica L. Tallo, Hanna M. Nohynek

10. Vaccine safety and adverse events: lessons learnt
Philippe Duclos, Adwoa D. Bentsi-Enchill, Dina Pfeifer

11. Sequential stages of clinical trials and overview of issues to be considered
John D. Clemens, R. Leon Ochiai

12. Practical aspects of phase 3 vaccine trials in developing countries
Brian Greenwood

13. Issues to be considered for the introduction of new vaccines into national vaccination programmes
Bjarne Bjorvatn

DRM-restrictions

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Keywords: MEDICAL / Public Health MED078000