St. John's Wort and its Active Principles in Depression and Anxiety

1. Introduction and historical overview
Walter E. Müller

2. Phytochemistry
Kurt Hostettmann, Jean-Luc Wolfender

3. St. John’s Wort and its active principles in depression and anxiety — A critical analysis of receptor binding studies
Marco Gobbi, Tiziana Mennini

4. Effects on transmitter uptake and their cellular and molecular basis
Kristina Treiber, Walter E. Müller

5. Modulation of neurotransmitter release and metabolism
Jan Kehr, Sven Ove Ögren, Takashi Yoshitake

6. Efficacy in behavioural models of antidepressant activity
Carla Gambarana, Daniela Giachetti

7. Comparative preclinical antidepressant activity of isolated constituents
Michael Nöldner

8. Hyperforin and efficacy in animal models for anxiety and cognition
Shyam S. Chatterjee

9. Pharmacokinetics and biopharmaceuticals
Mario Wurglics, Manfred Schubert-Zsilavecz

10. Clinical efficacy in depression
Siegfried Kasper

11. Clinical efficacy of St. John’s Wort in psychiatric disorders other than depression
Hans-Peter Volz

12. Side effects and drug interactions
Volker Schulz, Andreas Johne

13. Endocrinology of St. John’s Wort extract
Michael Franklin

DRM-restrictions

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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000