Sphingolipids in Disease

Part I. Sphingolipids in Cancer

1. Sphingosine Kinase/Sphingosine 1-Phosphate Signaling in Cancer Therapeutics and Drug Resistance
Shanmugam Panneer Selvam, Besim Ogretmen

2. Using ASMase Knockout Mice to Model Human Diseases
Guoqiang Hua, Richard Kolesnick

3. New Perspectives on the Role of Sphingosine 1-Phosphate in Cancer
Susan Pyne, Nigel J. Pyne

4. Sphingolipids and Response to Chemotherapy
Marie-Thérèse Dimanche-Boitrel, Amélie Rebillard

5. Lung Cancer and Lung Injury: The Dual Role of Ceramide
Tzipora Goldkorn, Samuel Chung, Simone Filosto

6. Sphingolipids’ Role in Radiotherapy for Prostate Cancer
Carla Hajj, Adriana Haimovitz-Friedman

Part II. Sphingolipids in Cardio-Reno-vascular Diseases

7. Sphingolipid Metabolism and Atherosclerosis
Xian-Cheng Jiang, Jing Liu

8. Cardiovascular Effects of Sphingosine-1-Phosphate (S1P)
Bodo Levkau

9. Cross Talk Between Ceramide and Redox Signaling: Implications for Endothelial Dysfunction and Renal Disease
Pin-Lan Li, Yang Zhang

Part III. Sphingolipids in Inflammation, Infection and Lung Diseases

10. Sphingolipids in Lung Endothelial Biology and Regulation of Vascular Integrity
Taimur Abbasi, Joe G. N. Garcia

11. Sphingolipids in Acute Lung Injury
Stefan Uhlig, Yang Yang

12. The Involvement of Sphingolipids in Chronic Obstructive Pulmonary Diseases
Irina Petrache, Daniela N. Petrusca

13. Ceramide in Cystic Fibrosis
Heike Grassmé, Joachim Riethmüller, Erich Gulbins

14. Regulation of the Sphingosine Kinase/Sphingosine 1-Phosphate Pathway
K. Alexa Orr Gandy, Lina M. Obeid

15. Bacterial Infections and Ceramide
Heike Grassmé, Katrin Anne Becker

16. Viral Infections and Sphingolipids
Jürgen Schneider-Schaulies, Sibylle Schneider-Schaulies

17. Ceramide in Plasma Membrane Repair
Annette Draeger, Eduard B. Babiychuk

18. Sphingolipids and Inflammatory Diseases of the Skin
Burkhard Kleuser, Lukasz Japtok

19. Sphingolipids in Obesity, Type 2 Diabetes, and Metabolic Disease
S. B. Russo, J. S. Ross, L. A. Cowart

Part IV. Sphingolipids in Neuro-psychiatry and Muscle Diseases

20. Neuronal Forms of Gaucher Disease
Einat B. Vitner, Anthony H. Futerman

21. Sphingolipids in Neuroinflammation
Laura Davies, Klaus Fassbender, Silke Walter

22. Sphingolipids in Psychiatric Disorders and Pain Syndromes
C. Mühle, M. Reichel, E. Gulbins, J. Kornhuber

23. Role of Sphingosine 1-Phosphate in Skeletal Muscle Cell Biology
Paola Bruni, Chiara Donati

Keywords: Biomedicine, Pharmacology/Toxicology, Cardiology, Cancer Research, Immunology, Neurosciences, Lipidology