Percutaneous Penetration Enhancers Drug Penetration Into/Through the Skin

Part I. Factors Influencing Percutaneous Drug Penetration

1. Basic Mathematics in Skin Absorption
Dominik Selzer, Ulrich F. Schaefer, Claus-Michael Lehr, Steffi Hansen

2. Occlusive Versus Nonocclusive Application in Transdermal Drug Delivery
Gamal M. Maghraby

3. Finite and Infinite Dosing
Wing Man Lau, Keng Wooi Ng

4. Non-formulation Parameters That Affect Penetrant-Skin-Vehicle Interactions and Percutaneous Absorption
Jeffrey E. Grice, Hamid R. Moghimi, Elizabeth Ryan, Qian Zhang, Isha Haridass, Yousuf Mohammed, Michael S. Roberts

5. The Influence of Emollients on Dermal and Transdermal Drug Delivery
V. R. Leite-Silva, Jeffrey E. Grice, Yousuf Mohammed, Hamid R. Moghimi, Michael S. Roberts

6. The Effects of Vehicle Mixtures on Transdermal Absorption: Thermodynamics, Mechanisms, Assessment, and Prediction
Jason T. Chittenden, Jim E. Riviere

7. Mechanistic Studies of Permeation Enhancers
S. Kevin Li, William I. Higuchi

8. High Throughput Screening of Transdermal Penetration Enhancers: Opportunities, Methods, and Applications
Amit Jain, Pankaj Karande, Samir Mitragotri

Part II. Methods for Measuring the Percutaneous Drug Penetration

9. Models, Methods, and Measurements in Transdermal Drug Delivery
Donald M. Cropek, Pankaj Karande

10. Human Native and Reconstructed Skin Preparations for In Vitro Penetration and Permeation Studies
Ulrich F. Schaefer, D. Selzer, S. Hansen, Claus-Michael Lehr

11. Stripping Procedures for Penetration Measurements of Topically Applied Substances
Jürgen Lademann, Sabine Schanzer, Heike Richter, Martina C. Meinke, Hans-Jürgen Weigmann, Alexa Patzelt

12. Application of EPR-spin Probes to Evaluate Penetration Efficiency, Storage Capacity of Nanotransporters, and Drug Release
Stefan F. Haag, Jürgen Lademann, Martina C. Meinke

Part II. Methods for Measuring the Percutaneous Drug Penetration

13. Confocal Raman Spectroscopy as a Tool to Investigate the Action of Penetration Enhancers Inside the Skin
Stéphanie Briançon, Marie-Alexandrine Bolzinger, Yves Chevalier

14. ATR-FTIR Spectroscopy and the Skin Barrier: Evaluation of Penetration-Enhancement Effects
Julia Covi-Schwarz, Victoria Klang, Claudia Valenta

15. Confocal Microscopy for Visualization of Skin Penetration
Mukul A. Ashtikar, Daya D. Verma, Alfred Fahr

16. Clinical Cutaneous Drug Delivery Assessment Using Single and Multiphoton Microscopy
Anthony P. Raphael, Tarl W. Prow

17. Corneoxenometry: A Bioassay Exploring Skin Barrier Breaching
Claudine Piérard-Franchimont, Trinh Hermanns-Lê, Gérald E. Piérard

18. Retardation Strategies for Sunscreen Agents
Katharina Bohnenblust-Woertz, Christian Surber

19. Retardation of Dermal Release by Film Forming Emulsions
Dominique Jasmin Lunter, Rolf Daniels

20. Penetration-Enhancement Strategies for Dermal and Transdermal Drug Delivery: An Overview of Recent Research Studies and Patents
Syed Sarim Imam, Mohammed Aqil

21. Perspectives on Dermal Delivery of Macromolecular Drugs
Marianna Foldvari, P. Kumar

22. Active Enhancement Methods in Transdermal Drug Delivery: Current Status and Future Perspectives
Ryan F. Donnelly

23. Efficacy, Safety and Targets in Topical and Transdermal Active and Excipient Delivery
Yousuf H. Mohammed, Hamid R. Moghimi, Shereen A. Yousef, Navin C. Chandrasekaran, Césa R. Bibi, Sinduja C. Sukumar, Jeffrey E. Grice, Wedad Sakran, Michael S. Roberts

24. Ethical Considerations in Research Involving Dermal and Transdermal Drug Delivery
Dusanka Krajnovic, Nina Dragicevic

Keywords: Medicine & Public Health, Dermatology, Pharmacology/Toxicology