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Humbert, Marc

Pharmacotherapy of Pulmonary Hypertension

Humbert, Marc - Pharmacotherapy of Pulmonary Hypertension, ebook

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ISBN: 9783642386640
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Table of contents

Part I. Pulmonary Hypertension: Conceptual Bases of the Disease

1. Definition and Classification of Pulmonary Hypertension
Marc Humbert, David Montani, Oleg V. Evgenov, Gérald Simonneau

2. Pulmonary Hypertension: Pathophysiology and Signaling Pathways
Bradley A. Maron, Joseph Loscalzo

3. Pulmonary Hypertension: Pathology
Peter Dorfmüller

4. Pulmonary Hypertension: Biomarkers
Christopher J. Rhodes, John Wharton, Martin R. Wilkins

5. Rodent Models of Group 1 Pulmonary Hypertension
John J. Ryan, Glenn Marsboom, Stephen L. Archer

Part II. Pulmonary Hypertension: Established Therapies

6. General Supportive Care
Ioana R. Preston

7. Calcium-Channel Blockers in Pulmonary Arterial Hypertension
Marie-Camille Chaumais, Elise Artaud Macari, Olivier Sitbon

8. Prostacyclins
Horst Olschewski

9. Endothelin Receptor Antagonists
Martine Clozel, Alessandro Maresta, Marc Humbert

10. Phosphodiesterase-5 Inhibitors
Barbara A. Cockrill, Aaron B. Waxman

11. Inhaled Nitric Oxide for the Treatment of Pulmonary Arterial Hypertension
Steven H. Abman

Part III. Pulmonary Hypertension: Novel Pathways and Emerging Therapies

12. Soluble Guanylate Cyclase Stimulators in Pulmonary Hypertension
Johannes-Peter Stasch, Oleg V. Evgenov

13. Therapeutics Targeting of Dysregulated Redox Equilibrium and Endothelial Dysfunction
Michael G. Risbano, Mark T. Gladwin

14. Rho-Kinase Inhibitors
Yoshihiro Fukumoto, Hiroaki Shimokawa

15. Serotonin Transporter and Serotonin Receptors
Serge Adnot, Amal Houssaini, Shariq Abid, Elisabeth Marcos, Valérie Amsellem

16. Targeting of Platelet-Derived Growth Factor Signaling in Pulmonary Arterial Hypertension
Eva Berghausen, Henrik Freyhaus, Stephan Rosenkranz

17. Emerging Molecular Targets for Anti-proliferative Strategies in Pulmonary Arterial Hypertension
Ly Tu, Christophe Guignabert

18. Anti-inflammatory and Immunosuppressive Agents in PAH
Jolyane Meloche, Sébastien Renard, Steeve Provencher, Sébastien Bonnet

19. Vasoactive Peptides and the Pathogenesis of Pulmonary Hypertension: Role and Potential Therapeutic Application
Reshma S. Baliga, Raymond J. MacAllister, Adrian J. Hobbs

20. Pulmonary Hypertension: Novel Pathways and Emerging Therapies Inhibitors of cGMP and cAMP Metabolism
Yassine Sassi, Jean-Sébastien Hulot

21. Pulmonary Hypertension: Old Targets Revisited (Statins, PPARs, Beta-Blockers)
Geoffrey Watson, Eduardo Oliver, Lan Zhao, Martin R. Wilkins

Part IV. Conclusions and Outlook

22. Pulmonary Hypertension: Current Management and Future Directions
Lewis J. Rubin

Keywords: Biomedicine, Pharmacology/Toxicology, Pharmaceutical Sciences/Technology, Internal Medicine, Pneumology/Respiratory System, Laboratory Medicine, Molecular Medicine

Author(s)
 
 
Publisher
Springer
Publication year
2013
Language
en
Edition
2013
Series
Handbook of Experimental Pharmacology
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9783642386640

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