Aon, Miguel A.

Systems Biology of Metabolic and Signaling Networks

Aon, Miguel A. - Systems Biology of Metabolic and Signaling Networks, ebook


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ISBN: 9783642385056
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Table of contents

Part I. Introduction

1. From Physiology, Genomes, Systems, and Self-Organization to Systems Biology: The Historical Roots of a Twenty-First Century Approach to Complexity
M. A. Aon, D. Lloyd, V. Saks

2. Complex Systems Biology of Networks: The Riddle and the Challenge
Miguel A. Aon

Part II. Systems Biology of Signaling Networks

3. The Control Analysis of Signal Transduction
Hans V. Westerhoff, Samrina Rehman, Fred C. Boogerd, Nilgun Yilmaz, Malkhey Verma

4. MicroRNAs and Robustness in Biological Regulatory Networks. A Generic Approach with Applications at Different Levels: Physiologic, Metabolic, and Genetic
Jacques Demongeot, Olivier Cohen, Alexandra Henrion-Caude

5. Dynamics of Mitochondrial Redox and Energy Networks: Insights from an Experimental–Computational Synergy
Sonia Cortassa, Miguel A. Aon

6. Adenylate Kinase Isoform Network: A Major Hub in Cell Energetics and Metabolic Signaling
Song Zhang, Emirhan Nemutlu, Andre Terzic, Petras Dzeja

Part III. Systems Biology of Cellular Structures and Fluxes

7. Moonlighting Function of the Tubulin Cytoskeleton: Macromolecular Architectures in the Cytoplasm
Judit Ovádi, Vic Norris

8. Metabolic Dissipative Structures
Ildefonso Mtz. Fuente

9. Systems Biology Approaches to Cancer Energy Metabolism
Alvaro Marín-Hernández, Sayra Y. López-Ramírez, Juan Carlos Gallardo-Pérez, Sara Rodríguez-Enríquez, Rafael Moreno-Sánchez, Emma Saavedra

Part IV. Systems Biology of Organ Function

10. Network Dynamics in Cardiac Electrophysiology
Zhilin Qu

11. Systems Level Regulation of Cardiac Energy Fluxes Via Metabolic Cycles: Role of Creatine, Phosphotransfer Pathways, and AMPK Signaling
Valdur Saks, Uwe Schlattner, Malgorzata Tokarska-Schlattner, Theo Wallimann, Rafaela Bagur, Sarah Zorman, Martin Pelosse, Pierre Dos Santos, François Boucher, Tuuli Kaambre, Rita Guzun

Part V. Systems Biology of Microorganisms

12. Temporal Partitioning of the Yeast Cellular Network
Douglas B. Murray, Cornelia Amariei, Kalesh Sasidharan, Rainer Machné, Miguel A. Aon, David Lloyd

13. Systems Biology and Metabolic Engineering in Bacteria
Johannes Geiselmann

Keywords: Life Sciences, Systems Biology, Computer Appl. in Life Sciences, Biological Networks, Systems Biology, Metabolomics, Proteomics, Biophysics and Biological Physics

Publication year
Springer Series in Biophysics
Page amount
10 pages
Natural Sciences

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