Disruption of Protein-Protein Interfaces

1. Drug Discovery by Targeting Protein–Protein Interactions
Laura Bettinetti, Matteo Magnani, Alessandro Padova

2. Protein–Protein Interaction Inhibitors: Case Studies on Small Molecules and Natural Compounds
Stefania Ferrari, Federica Pellati, Maria Paola Costi

3. Disrupting Protein–Protein Interfaces Using GRID Molecular Interaction Fields
Simon Cross, Massimo Baroni, Francesco Ortuso, Stefano Alcaro, Gabriele Cruciani

4. NMR as a Tool to Target Protein–Protein Interactions
Rebecca Del Conte, Daniela Lalli, Paola Turano

5. Protein–Protein Interactions in the Solid State: The Troubles of Crystallizing Protein–Protein Complexes
Stefano Mangani

6. Fluorescence Observables and Enzyme Kinetics in the Investigation of PPI Modulation by Small Molecules: Detection, Mechanistic Insight, and Functional Consequences
Glauco Ponterini

Keywords: Chemistry, Organic Chemistry