Erdmann, Volker A.

From Nucleic Acids Sequences to Molecular Medicine

Erdmann, Volker A. - From Nucleic Acids Sequences to Molecular Medicine, ebook


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Table of contents

1. RNAissance
Juergen Brosius

2. Nucleic Acids as Therapeutics
Saraswat Pushpendra, Pareek Arvind, Bhandari Anil

3. Thio Effects as a Tool for Mechanistic Studies of the Cleavage of RNA Phosphodiester Bonds: The Chemical Basis
Mikko Ora, Tuomas Lönnberg, Harri Lönnberg

4. Off-Target Effects and Safety Aspects of Phosphorothioate Oligonucleotides
Martina Stessl, Christian R. Noe, Johannes Winkler

5. Oligonucleotide Conjugates: Rationale, Synthesis, and Applications
Yashveer Singh, Pierre Murat, Nicolas Spinelli, Eric Defrancq

6. CRISPR: A Bacterial Immunity System Based on Small RNAs
Rolf Wagner, Ümit Pul

7. Antisense Technology: From Unique Laboratory Tool to Novel Anticancer Treatments
Christine Cresce, Colin Way, Mateusz Rytelewski, Saman Maleki Vareki, Supritha Nilam, Mark D. Vincent, James Koropatnick, Peter J. Ferguson

8. Antisense-Mediated Reduction of Eukaryotic Noncoding RNAs
Xue-hai Liang, Timothy A. Vickers, Stanley T. Crooke

9. Antisense Oligonucleotides in the Treatment of Malignant Gliomas
Gerardo Caruso, Mariella Caffo, Giuseppe Raudino, Federica Raudino, Mario Venza, Francesco Tomasello

10. Natural Antisense Transcripts Mediate Regulation of Gene Expression
Marco Magistri, Mohammad Ali Faghihi

11. Activation and Deactivation of Antisense and RNA Interference Function with Light
Jeane M. Govan, Alexander Deiters

12. Ribozymes as Molecular Biology Reagents
Sanchita Bhadra, Arti Pothukuchy, Andrew Ellington

13. RNA Technologies for Mitochondrial Genetics
André Dietrich, Katarzyna Rolle, Marta Gabryelska, Eliza Wyszko, Romain Val, Maciej Szymanski, Clarisse Valentin, Anne Cosset, Jan Barciszewski

14. RNA-Based Therapies for Inherited Metabolic Diseases
Belén Pérez, Magdalena Ugarte, Lourdes R. Desviat

15. RNA-Cleaving DNA Enzymes and Their Potential Therapeutic Applications as Antibacterial and Antiviral Agents
P. I. Pradeepkumar, Claudia Höbartner

16. Hammerhead Ribozymes Against Virus and Viroid RNAs
Alberto Carbonell, Ricardo Flores, Selma Gago

17. Suppression of Hepatitis C Viral Genome Replication with RNA-Cleaving Deoxyribozyme
Dal-Hee Min, Dong-Eun Kim

18. Design of Synthetic shRNAs for Targeting Hepatitis C: A New Approach to Antiviral Therapeutics
Brian H. Johnston, Qing Ge

19. The Diverse Active Sites in Splicing, Debranching, and MicroRNA Processing Around RNA Phosphodiester Bonds
Sourav Kumar Dey, Eduardo Paredes, Molly Evans, Subha R. Das

20. MicroRNAs and Their Antagonists as Novel Therapeutics
Jeppe Vinther, Jakob Lewin Rukov, Noam Shomron

21. microRNAs in Human Diseases and Viral Infections
Alessandra Mescalchin, Tobias Restle

22. Dysregulation of MicroRNA Expression and Human Diseases?
To-Ha Thai

23. Noncoding RNAs: Identification of Cancer-Associated MicroRNAs
Muller Fabbri, George A. Calin

24. Targeting Non-coding RNAs for Cancer Therapy
Satya K. Kota, Savithri Balasubramanian

25. MicroRNA Pathways in Drosophila

Geetanjali Chawla, Nicholas S. Sokol

26. Viroids: The Smallest Known Infectious Agents Cause Accumulation of Viroid-Specific Small RNAs
Jaroslav Matoušek, Detlev Riesner, Gerhard Steger

Keywords: Biomedicine, Molecular Medicine, Nucleic Acid Chemistry, Human Genetics

Publication year
RNA Technologies
Page amount
663 pages
Medicine, Health Care, Mode

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