Prevention of Bone Metastases

1. Preclinical Models that Illuminate the Bone Metastasis Cascade
Geertje Horst, Gabri Pluijm

2. The Role of Bone Microenvironment, Vitamin D and Calcium
Daniele Santini, Francesco Pantano, Bruno Vincenzi, Giuseppe Tonini, Francesco Bertoldo

3. Bisphosphonates: Prevention of Bone Metastases in Breast Cancer
Michael Gnant, Peter Dubsky, Peyman Hadji

4. Bisphosphonates: Prevention of Bone Metastases in Lung Cancer
Lynn Decoster, Filippo Marinis, Kostas Syrigos, Vera Hirsh, Kristiaan Nackaerts

5. Bisphosphonates: Prevention of Bone Metastases in Prostate Cancer
Fred Saad, Jean-Baptiste Lattouf

6. Targeting Bone in Myeloma
G. J. Morgan, Ping Wu

7. Combinations of Bisphosphonates and Classical Anticancer Drugs: A Preclinical Perspective
Maria Michailidou, Ingunn Holen

8. Perspectives in the Elderly Patient: Benefits and Limits of Bisphosphonates and Denosumab
Daniele Santini, Maria Elisabetta Fratto, Matti Aapro

9. Denosumab: First Data and Ongoing Studies on the Prevention of Bone Metastases
Roger von Moos, Tomas Skacel

10. Diagnostic and Prognostic Use of Bone Turnover Markers
Markus Joerger, Jens Huober

11. Osteolytic and Osteoblastic Bone Metastases: Two Extremes of the Same Spectrum?
Angelica Ortiz, Sue-Hwa Lin

Keywords: Medicine & Public Health, Oncology, Surgical Oncology