Denman, Robert B.

Modeling Fragile X Syndrome

Denman, Robert B. - Modeling Fragile X Syndrome, ebook


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ISBN: 9783642216497
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Table of contents

1. Introduction: Reminiscing on Models and Modeling
Robert B. Denman

2. Probing Astrocyte Function in Fragile X Syndrome
Shelley Jacobs, Connie Cheng, Laurie C. Doering

3. Neural Stem Cells
Maija Castrén

4. Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System
Theodore J. Price, Ohannes K. Melemedjian

5. The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome
Stefan Kindler, Hans-Jürgen Kreienkamp

6. Behavior in a Drosophila Model of Fragile X
Sean M. McBride, Aaron J. Bell, Thomas A. Jongens

7. Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome
Charles R. Tessier, Kendal Broadie

8. Fragile X Mental Retardation Protein and Stem Cells
Abrar Qurashi, Xuekun Li, Peng Jin

9. Manipulating the Fragile X Mental Retardation Proteins in the Frog
Marc-Etienne Huot, Nicolas Bisson, Thomas Moss, Edouard W. Khandjian

10. Exploring the Zebra Finch Taeniopygia guttata as a Novel Animal Model for the Speech–Language Deficit of Fragile X Syndrome
Claudia Winograd, Stephanie Ceman

11. Neuroendocrine Alterations in the Fragile X Mouse
Abdeslem El Idrissi, Xin Yan, William L’Amoreaux, W. Ted Brown, Carl Dobkin

12. Taking STEPs Forward to Understand Fragile X Syndrome
Susan M. Goebel-Goody, Paul J. Lombroso

Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease
Bojana Zupan, Miklos Toth

14. Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome
Michael R. Hunsaker, Gloria Arque, Robert F. Berman, Rob Willemsen, Renate K. Hukema

15. Clinical Aspects of the Fragile X Syndrome
W. Ted Brown

16. Fragile X Syndrome: A Psychiatric Perspective
Michael R. Tranfaglia

17. Fragile X Syndrome and Targeted Treatment Trials
Randi Hagerman, Julie Lauterborn, Jacky Au, Elizabeth Berry-Kravis

18. The Fragile X-Associated Tremor Ataxia Syndrome
Flora Tassone, Randi Hagerman

19. Vignettes: Models in Absentia
Robert B. Denman

Keywords: Life Sciences, Cell Biology, Human Genetics, Molecular Medicine, Neurobiology, Stem Cells, Gene Therapy

Publication year
Results and Problems in Cell Differentiation
Page amount
11 pages
Natural Sciences

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