Drug Transporters

1. Uptake Transporters of the Human OATP Family
Jörg König

2. In Vitro and In Vivo Evidence of the Importance of Organic Anion Transporters (OATs) in Drug Therapy
Gerhard Burckhardt, Birgitta Christina Burckhardt

3. Organic Cation Transporters (OCTs, MATEs), In Vitro and In Vivo Evidence for the Importance in Drug Therapy
Anne T. Nies, Hermann Koepsell, Katja Damme, Matthias Schwab

4. Role of the Intestinal Bile Acid Transporters in Bile Acid and Drug Disposition
Paul A. Dawson

5. The Role of the Sodium-Taurocholate Cotransporting Polypeptide (NTCP) and of the Bile Salt Export Pump (BSEP) in Physiology and Pathophysiology of Bile Formation
Bruno Stieger

6. P-glycoprotein: Tissue Distribution, Substrates, and Functional Consequences of Genetic Variations
Ingolf Cascorbi

7. Importance of P-glycoprotein for Drug–Drug Interactions
Hartmut Glaeser

8. Multidrug Resistance Proteins (MRPs, ABCCs): Importance for Pathophysiology and Drug Therapy
Dietrich Keppler

9. In Vitro and In Vivo Evidence for the Importance of Breast Cancer Resistance Protein Transporters (BCRP/MXR/ABCP/ABCG2)
Henriette E. Meyer zu Schwabedissen, Heyo K. Kroemer

10. Molecular Mechanisms of Drug Transporter Regulation
Rommel G. Tirona

11. In Vivo Probes of Drug Transport: Commonly Used Probe Drugs to Assess Function of Intestinal P-glycoprotein (ABCB1) in Humans
Stefan Oswald, Bernd Terhaag, Werner Siegmund

Keywords: Biomedicine, Pharmacology/Toxicology, Pharmaceutical Sciences/Technology, Human Physiology, Drug Resistance, Hepatology, Nephrology