The Ubiquitin System in Health and Disease

1. Crosstalk Between the SUMO and Ubiquitin Pathways
T. Hunter, H. Sun

2. A Tale of Two Giant Proteases
B. Rockel, W. Baumeister

3. Molecular Genetics of the Ubiquitin-Proteasome System: Lessons from Yeast
M. Hochstrasser, M. Deng, A. R. Kusmierczyk, X. Li, S. G. Kreft, T. Ravid, M. Funakoshi, M. Kunjappu, Y. Xie

4. Less Is More: How Protein Degradation Regulates Muscle Development
T. Hoppe

5. Transcriptional Control and the Ubiquitin–Proteasome System
A. Leung, F. Geng, A. Daulny, G. Collins, P. Guzzardo, W. P. Tansey

6. Ubiquitination of Myc: Proteasomal Degradation and Beyond
J. Müller, M. Eilers

7. Regulation of Apoptosis and Cytokinesis by the Anti-apoptotic E2/E3 Ubiquitin-Ligase BRUCE
C. Pohl, S. Jentsch

8. Dissecting Roles of Ubiquitination in the p53 Pathway
J. Shan, C. Brooks, N. Kon, M. Li, W. Gu

9. Regulation of T Cell Differentiation and Allergic Responses by the E3 Ubiquitin Ligase Itch
Y.-C. Liu

10. Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases
J. Huang, L. Tsvetkov, K. Qu, S. Daniel-Issakani, D. G. Payan

11. Inhibiting Hdm2 and Ubiquitin-Activating Enzyme: Targeting the Ubiquitin Conjugating System in Cancer
A. M. Weissman, Y. Yang, J. Kitagaki, C. A. Sasiela, J. A. Beutler, B. R. O'Keefe

Keywords: MEDICAL / Public Health MED078000