Molecular Chaperones in Health and Disease

1. Chaperones in Preventing Protein Denaturation in Living Cells and Protecting Against Cellular Stress
H.H. Kampinga

2. Feedback Regulation of the Heat Shock Response
R. Voellmy

3. Protein Folding in the Endoplasmic Reticulum and the Unfolded Protein Response
K. Zhang, R.J. Kaufman

4. Molecular Chaperones in Signal Transduction
M. Gaestel

5. Chaperoning of Glucocorticoid Receptors
W.B. Pratt, Y. Morishima, M. Murphy, M. Harrell

6. Heat Shock Response: Lessons from Mouse Knockouts
E.S. Christians, I.J. Benjamin

7. HSFs in Development
M. Morange

8. Heat Shock Proteins: Endogenous Modulators of Apoptotic Cell Death
C. Didelot, E. Schmitt, M. Brunet, L. Maingret, A. Parcellier, C. Garrido

9. Protein Aggregation as a Cause for Disease
T. Scheibel, J. Buchner

10. The Role of Chaperones in Parkinson’s Disease and Prion Diseases
K.F. Winklhofer, J. Tatzelt

11. Chaperoning Oncogenes: Hsp90 as a Target of Geldanamycin
L. Neckers

12. Heat Shock Proteins in Immunity
G. Multhoff

13. Molecular Chaperones and Cancer Immunotherapy
X.-Y. Wang, J.G. Facciponte, J.R. Subjeck

14. Hsp90 Inhibitors in the Clinic
S. Pacey, U. Banerj, I. Judson, P. Workman

15. Pharmacological Targeting of Catalyzed Protein Folding: The Example of Peptide Bond cis/trans Isomerases
F. Edlich, G. Fischer

16. Chemical Chaperones: Mechanisms of Action and Potential Use
E. Papp, P. Csermely

17. Pharmacological Modulation of the Heat Shock Response
C. Soti, P. Csermely

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Keywords: TECHNOLOGY & ENGINEERING / Biomedical TEC059000