Cohen, Patricia T.W.
Inhibitors of Protein Kinases and Protein Phosphates
1. Protein Kinase Inhibitors for the Treatment of Disease: The Promise and the Problems
P. Cohen
Part I. General Aspects of PKs Inhibition
2. New Design Strategies for Ligands That Target Protein Kinase-Mediated Protein-Protein Interactions
D. S. Lawrence
Part II. Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases
3. The Paullones: A Family of Pharmacological Inhibitors of Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3
L. Meijer, M. Leost, O. Lozach, S. Schmitt, C. Kunick
4. Pharmacological Potential of p38 MAPK Inhibitors
S. Kumar, S. M. Blake
5. Inhibitors of PKA and Related Protein Kinases
M. Gaßel, C. Breitenlechner, S. Herrero, R. Engh, D. Bossemeyer
6. Inhibitors of Protein Kinase CK2: Structural Aspects
R. Battistutta, S. Sarno, G. Zanotti
7. Aminoglycoside Kinases and Antibiotic Resistance
D. H. Fong, D. L. Burk, A. M. Berghuis
Part III. Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases
8. Protein Tyrosine Phosphatases as Therapeutic Targets
A. Cheng, N. Uetani, C. Lampron, M. L. Tremblay
9. Structure-Based Design of Protein Tyrosine Phosphatase Inhibitors
N. P. H. Møller, H. S. Andersen, C. B. Jeppesen, L. F. Iversen
10. Biological Validation of the CD45 Tyrosine Phosphatase as a Pharmaceutical Target
D. R. Alexander
11. Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activity
R. E. Honkanen
Part IV. Inhibitors in Clinical Use or Advanced Clinical Trials
12. Clinical Immunosuppression using the Calcineurin-Inhibitors Ciclosporin and Tacrolimus
N. R. Banner, H. Lyster, M. H. Yacoub
13. Targeted Therapy with Imatinib: An Exception or a Rule?
D. Fabbro, G. Fendrich, V. Guez, T. Meyer, P. Furet, J. Mestan, J. D. Griffin, P. W. Manley, S. W. Cowan-Jacob
14. Clinical Aspects of Imatinib Therapy
B. J. Druker
15. Isoquinolinesulfonamide: A Specific Inhibitor of Rho-Kinase and the Clinical Aspect of Anti-Rho-Kinase Therapy
H. Hidaka, Y. Suzuki, M. Shibuya, Y. Sasaki
16. Discovery and Development of Iressa: The First in a New Class of Drugs Targeted at the Epidermal Growth Factor Receptor Tyrosine Kinase
A. E. Wakeling
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- Author(s)
- Cohen, Patricia T.W.
- Pinna, Lorenzo A.
- Publisher
- Springer
- Publication year
- 2005
- Language
- en
- Edition
- 1
- Category
- Medicine, Health Care, Mode
- Format
- Ebook
- eISBN (PDF)
- 9783540266709