Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development

Presents the most effective catalytic reactions in use today, with a special focus on process intensification, sustainability, waste reduction, and innovative methods

This book demonstrates the importance of efficient catalytic transformations for producing pharmaceutically active molecules. It presents the key catalytic reactions and the most efficient catalytic processes, including their significant advantages over compared previous methods. It also places a strong emphasis on asymmetric catalytic reactions, process intensification (PI), sustainability and waste mitigation, continuous manufacturing processes as enshrined by continuous flow catalysis, and supported catalysis.

Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development offers chapters covering: Catalysis and Prerequisites for the Modern Pharmaceutial Industry Landscape; Catalytic Process Design - The Industrial Perspective; Hydrogenation, Hydroformylation and Other Reductions; Oxidation; ; Catalytic Addition Reactions; Catalytic Cross-Coupling Reactions; Catalytic Metathesis Reactions; Catalytic Cycloaddition Reactions: Coming Full-Circle; Catalytic Cyclopropanation Reactions; Catalytic C-H insertion Reactions; Phase Transfer Catalysis; and Biocatalysis.

-Provides the reader with an updated clear view of the current state of the challenging field of catalysis for API production
-Focuses on the application of catalytic methods for the synthesis of known APIs
-Presents every key reaction, including Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, and many more
-Includes recent patent literature for completeness

Covering a topic of great interest for synthetic chemists and R&D researchers in the pharmaceutical industry, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development is a must-read for every synthetic chemist working with APIs.

Keywords:

pharmaceuticals, chemistry, pharmaceutical ingredients, pharmaceutical synthesis, synthetic chemistry, chemical synthesis, chemical ingredients in pharmaceuticals, pharmaceutical chemistry, medicinal chemistry, organometallics, the chemical industry, catalytic chemistry, chemical processing, catalyst processes, Active Pharmaceutical Ingredient (API), catalytic organic synthesis, pharmaceutics, drug synthesis, catalytic processes for drugs, catalytic reactions, drug process intensification, drug sustainability, drug waste reduction, asymmetric catalytic reactions, synthesis of chiral amines, Diels-Alder, CH Insertions, Metal-catalytic coupling-reactions, biocatalysis, synthetic biology, Active Pharmaceutical Ingredients in Synthesis: Catalytic Processes in Research and Development