Asymmetric Synthesis of Three-Membered Rings

The first handbook to focus on the asymmetric synthesis of different types of three-membered rings.
The outstanding and experienced authors have an excellent international reputation and cover cyclopropanes, epoxides and aziridines as well as chiral oxaziridines in equal measure. To this end, they describe in detail different synthetic approaches starting with chiral substrates as well as the application of chiral metal- or organocatalysts. Furthermore, methods for the kinetic resolution of initially racemic products are treated alongside recent advances and novel developments in established techniques for the synthesis of three-membered rings.
With its structured composition this is of high interest to scientists in methodological and natural product synthesis as well as those in industrial and pharmaceutical chemistry.

Keywords: cyclopropane, epoxide, aziridine, oxaziridine, cyclization, Simmons-Smith, MIRC, kinetic resolution, Darzens reaction, azirine, thiirane, catalysis