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Handler, Norbert

Drug Selectivity: An Evolving Concept in Medicinal Chemistry

Handler, Norbert - Drug Selectivity: An Evolving Concept in Medicinal Chemistry, ebook

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The book "Drug Selectivity - An Evolving Concept in Medicinal Chemistry" provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process.
The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.

Keywords: selective unselective drugs medicinal chemistry multi-target multi-specific combination drugs clinical development drug formulation regulatory aspects selective optimization of side activities SOSA merged multiple ligands fixed-dose combinations

Editor
 
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2015
Language
en
Edition
1
Series
Methods & Principles in Medicinal Chemistry
Page amount
536 pages
Category
Medicine, Health Care, Mode
Format
Ebook
Printed ISBN
9783527674411

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