Abdel-Meguid, Sherin S.
Protein Crystallography in Drug Discovery
Here, researchers from leading pharmaceutical companies present valuable first-hand information, much of it published for the first time. They discuss strategies to derive high-resolution structures for such important target protein classes as kinases or proteases, as well as selected examples of successful protein crystallographic studies. A special section on recent methodological developments, such as for high-throughput crystallography and microcrystallization, is also included.
A valuable companion for crystallographers involved in protein structure determination as well as drug developers pursuing the structure-based approach for use in their daily work.
Keywords: SCIENCE / Chemistry / Industrial & Technical SCI013060
- Author(s)
- Abdel-Meguid, Sherin S.
- Babine, Robert E.
- Folkers, Gerd
- Kubinyi, Hugo
- Mannhold, Raimund
- Publisher
- John Wiley and Sons, Inc.
- Publication year
- 2006
- Language
- en
- Edition
- 1
- Series
- Methods and Principles in Medicinal Chemistry
- Page amount
- 278 pages
- Category
- Technology, Energy, Traffic
- Format
- Ebook
- eISBN (PDF)
- 9783527606351
- Printed ISBN
- 9783527306787