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Buschmann, Helmut

Epigenetic Drug Discovery

Buschmann, Helmut - Epigenetic Drug Discovery, ebook

182,15€

Ebook, ePUB with Adobe DRM
ISBN: 9783527809264
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Printing144 pages with an additional page accrued every 6 hours, capped at 144 pages
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This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins.
Presented in three parts - Introduction to Epigenetics, General Aspects and Methodologies, and Epigenetic Target Classes - it covers everything any drug researcher would need in order to know about targeting epigenetic mechanisms of disease.
Epigenetic Drug Discovery is an important resource for medicinal chemists, pharmaceutical researchers, biochemists, molecular biologists, and molecular geneticists.

Keywords:

epigenetic; drug discovery; genetics; drug development; physical sciences; medicinal chemistry methods; epigenetic targets; epigenetic targets in drug discovery; medicinal chemistry principles; pharmacology; genetic cells; targeting the human genome; epigenetic regulation; drug targeting for disease; drug targeting for epigenetics; epigenetic inhibitors in cancer; structural biology of epigenetic targets; approaches to epigenetics; peptide microarrays for epigenetic targets; target fishing; computer based drug design; chemoproteomics; chemical probe development; sirtuins, methyl-lysine reader proteins; parasitic targets; HDAC inhibitors; methyltransferases; demethylases LSD1; JMJD; histone acetyltransferases; BRD bromodomains; DNA modifying enzymes

, Molecular Genetics, Biochemistry (Chemical Biology), Molecular Genetics, Biochemistry (Chemical Biology)
Editor
 
 
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2018
Language
en
Edition
1
Series
Methods and Principles in Medicinal Chemistry
Page amount
480 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9783527809264
Printed ISBN
9783527343140

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