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Folkers, Gerd

Animal Models for Human Cancer: Discovery and Development of Novel Therapeutics

Folkers, Gerd - Animal Models for Human Cancer: Discovery and Development of Novel Therapeutics, ebook

184,15€

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ISBN: 9783527695898
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Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results.
Following a short historical introduction and a discussion of the ethics surrounding animal experiments, the book describes correct study design as well as the handling and housing of animals. It then goes on to describe the animal models available for different cancer types, from natural cancer models in mice and dogs to humanized animals. An evaluation of previously unpublished long-term data from the Swiss canine and feline cancer registry is also included. The final part of the book reviews the lessons learned over the last decade on how to interpret data from animal studies for improving human therapy and gives recommendations for future drug development.

Keywords: animal studies experiments models cancer therapy reproducibility interpretation Swiss registry, animal studies experiments models cancer therapy reproducibility interpretation Swiss registry, animal studies experiments models cancer therapy reproducibility interpretation Swiss registry, Drug Discovery & Development

Editor
 
 
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2016
Language
en
Edition
1
Series
Methods and Principles in Medicinal Chemistry
Page amount
650 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9783527695898
Printed ISBN
9783527339976

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