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Cerdan, Rachel

Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery

Cerdan, Rachel - Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery, ebook

174,00€

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ISBN: 9783527694112
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Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

Keywords: parasites; metabolic analysis; antiparasitic; drug discovery; design pathway; modelling, Parasitology, Cellular & Molecular Medicine, Parasitology, Cellular & Molecular Medicine

Editor
 
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2016
Language
en
Edition
1
Series
Drug Discovery in Infectious Diseases
Page amount
576 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9783527694112
Printed ISBN
9783527339044

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