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Folkers, Gerd

Thermodynamics and Kinetics of Drug Binding, Volume 65

Folkers, Gerd - Thermodynamics and Kinetics of Drug Binding, Volume 65, ebook

156,25€

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ISBN: 9783527673056
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This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects.

Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.

Keywords: drug-receptor interaction binding mechanism drugs bioactive molecules experimental computational methods binding mode, Drug Discovery & Development

Editor
 
 
 
 
Publisher
John Wiley and Sons, Inc.
Publication year
2015
Language
en
Edition
1
Series
Methods and Principles in Medicinal Chemistry
Page amount
480 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9783527673056
Printed ISBN
9783527335824

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