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Gemma, Sandra

Structure-based Design of Drugs and Other Bioactive Molecules: Tools and Strategies

Gemma, Sandra - Structure-based Design of Drugs and Other Bioactive Molecules: Tools and Strategies, ebook

111,60€

Ebook, ePUB with Adobe DRM
ISBN: 9783527665235
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Printing132 pages with an additional page accrued every 6 hours, capped at 132 pages
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In contrast to previous texts focusing on either computational, structural or synthetic methods, this one-of-a-kind guide integrates all three skill sets for a complete picture of contemporary structure-based design.
As a result, this practical book demonstrates how to develop a high-affinity ligand with drug-like properties for any given drug target for which a high-resolution structure exists. The authors, both of whom have successfully designed drug-like molecules that were later developed into marketed drugs, use numerous examples of recently developed drugs to present best practice in structure-based drug design with the novice in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design.

Keywords: Drug Discovery & Development

Author(s)
 
Publisher
John Wiley and Sons, Inc.
Publication year
2014
Language
en
Edition
1
Page amount
440 pages
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (ePUB)
9783527665235
Printed ISBN
9783527333653

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