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Dörwald, Florencio Zaragoza

Lead Optimization for Medicinal Chemists: Pharmacokinetic Properties of Functional Groups and Organic Compounds

Dörwald, Florencio Zaragoza - Lead Optimization for Medicinal Chemists: Pharmacokinetic Properties of Functional Groups and Organic Compounds, ebook

155,45€

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ISBN: 9783527645657
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Printing187 pages with an additional page accrued every 4 hours, capped at 187 pages
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Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and synonyms to facilitate the location of any drug or functional group in the book.
This compact working guide provides a wealth of information on the ways small structural modifications affect the pharmacokinetic properties of organic compounds, and offers plentiful, fact-based inspiration for the development of new drugs. This book is mainly aimed at medicinal chemists, but may also be of interest to graduate students in chemical or pharmaceutical sciences, preparing themselves for a job in the pharmaceutical industry, and to healthcare professionals in need of pharmacokinetic data.

Keywords: drugs, drug development, drug discovery, drug optimization, lead optimization, medicinal chemistry, structure-activity relationships, pharmacokinetics, pharmacology, toxicology, Methods - Synthesis & Techniques, Pharmacology & Pharmaceutical Medicine, Methods - Synthesis & Techniques, Pharmacology & Pharmaceutical Medicine

Author(s)
Publisher
John Wiley and Sons, Inc.
Publication year
2012
Language
en
Edition
1
Page amount
622 pages
Category
Natural Sciences
Format
Ebook
eISBN (ePUB)
9783527645657
Printed ISBN
9783527332267

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