Login

Almeida, Luís Pereira de

Polyglutamine Disorders

Almeida, Luís Pereira de - Polyglutamine Disorders, ebook

230,65€

Ebook, PDF with Adobe DRM
ISBN: 9783319717791
DRM Restrictions

PrintingNot allowed
Copy to clipboardNot allowed

Table of contents

1. Clinical Features of Huntington’s Disease
Rhia Ghosh, Sarah J. Tabrizi

2. Genetic Rodent Models of Huntington Disease
J. Stricker-Shaver, A. Novati, L. Yu-Taeger, H. P. Nguyen

3. Mitochondrial Dysfunction in Huntington’s Disease
Catarina Carmo, Luana Naia, Carla Lopes, A. Cristina Rego

4. RNA Related Pathology in Huntington’s Disease
Andreas Neueder, Gillian P. Bates

5. X-Linked Spinal and Bulbar Muscular Atrophy: From Clinical Genetic Features and Molecular Pathology to Mechanisms Underlying Disease Toxicity
Constanza J. Cortes, Albert R. Spada

6. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies
Judit M. Pérez Ortiz, Harry T. Orr

7. Spinocerebellum Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics
Xiaofei Du, Christopher Manuel Gomez

8. Spinocerebellar Ataxia Type 2
Daniel R. Scoles, Stefan M. Pulst

9. Molecular Mechanisms and Therapeutic Strategies in Spinocerebellar Ataxia Type 7
Alice Karam, Yvon Trottier

10. Spinocerebellar Ataxia Type 17 (SCA17)
Yasuko Toyoshima, Hitoshi Takahashi

11. The Neuropathology of Spinocerebellar Ataxia Type 3/Machado-Joseph Disease
Arnulf H. Koeppen

12. Origins and Spread of Machado-Joseph Disease Ancestral Mutations Events
Sandra Martins, Jorge Sequeiros

13. Clinical Features of Machado-Joseph Disease
Nuno Mendonça, Marcondes C. França, António Freire Gonçalves, Cristina Januário

14. Polyglutamine-Independent Features in Ataxin-3 Aggregation and Pathogenesis of Machado-Joseph Disease
Ana Luisa Carvalho, Alexandra Silva, Sandra Macedo-Ribeiro

15. Animal Models of Machado-Joseph Disease
Jana Schmidt, Thorsten Schmidt

16. Towards the Identification of Molecular Biomarkers of Spinocerebellar Ataxia Type 3 (SCA3)/Machado-Joseph Disease (MJD)
Manuela Lima, Mafalda Raposo

17. Planning Future Clinical Trials for Machado-Joseph Disease
Jonas Alex Morales Saute, Laura Bannach Jardim

18. Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis

Clévio Nóbrega, Ana Teresa Simões, Joana Duarte-Neves, Sónia Duarte, Ana Vasconcelos-Ferreira, Janete Cunha-Santos, Dina Pereira, Magda Santana, Cláudia Cavadas, Luís Pereira Almeida

19. Pharmacological Therapies for Machado-Joseph Disease
Sara Duarte-Silva, Patrícia Maciel

20. Gene Therapies for Polyglutamine Diseases
Carlos A. Matos, Vítor Carmona, Udaya-Geetha Vijayakumar, Sara Lopes, Patrícia Albuquerque, Mariana Conceição, Rui Jorge Nobre, Clévio Nóbrega, Luís Pereira Almeida

21. Stem Cell-Based Therapies for Polyglutamine Diseases
Liliana S. Mendonça, Isabel Onofre, Catarina Oliveira Miranda, Rita Perfeito, Clévio Nóbrega, Luís Pereira Almeida

Keywords: Biomedicine, Neurosciences, Neurology, Gene Function

Editor
 
Publisher
Springer
Publication year
2018
Language
en
Edition
1
Series
Advances in Experimental Medicine and Biology
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9783319717791
Printed ISBN
978-3-319-71778-4

Similar titles