Antibody Therapy

1. The Clinical Translation of Intravenous Immunoglobulin from Substitution to Immunomodulation
Paul Imbach

Part I. Update of Substitutive and Immunomodulatory Antibodies/Drugs Indications

2. From Immune Substitution to Immuno-modulation
Volker Wahn

3. Manual of Primary and Secondary Immunodeficiencies
Paul Imbach, Volker Wahn

4. Manual of Intravenous and Subcutaneous IgG Indications in Autoimmune Diseases
Paul Imbach

5. Anti-D: A Type of IVIg
Ramsha Khan, Alan H. Lazarus

6. Mechanisms of Action and Immunomodulation by IVIg
Alan H. Lazarus

7. Immunomodulatory Drugs and Monoclonal Antibodies
Howard A. Liebman

8. Use of Intravenous Immunoglobulin in Neurology
Marinos C. Dalakas

9. Use of Intravenous Immunoglobulin in Dermatology
Jochen H. O. Hoffmann, Alexander H. Enk

Part II. Basics of IgG Concentrates

10. Historical Aspects of Polyclonal IgG Preparations
Volker Wahn, Peter Späth

11. Basics of Immunoglobulins as Effector Molecules and Drugs
Tchavdar L. Vassilev, Victor Kostov, Stephan Gunten, Anastas D. Pashov

12. Essentials of theProduction of Safe and Efficacious State-of-the-Art Polyclonal IgG Concentrates
Peter J. Späth

13. Current IgG Products and Future Perspectives
Peter J. Späth

Part III. Immune Thrombocytopenia: The First Immunomodulatory IgG Treatment

14. Updates in Immune Thrombocytopenia: Terminology, Immunomodulation and Platelet Stimulation, and Clinical Guidelines and Management
Cindy Neunert

15. Health-Related Quality of Life in Patients with Immune Thrombocytopenia
Robert J. Klaassen, Nancy L. Young

16. ITP in Childhood: Predictors of Disease Duration
Carolyn M. Bennett

17. Immune Functions of Platelets
Rick Kapur, John W. Semple

18. Thrombopoietin Receptor Agonists: Characteristics, Adverse Effects, and Indications
Jenny Despotovic, Amanda Grimes

19. Registries in Immune Thrombocytopenia: The History of theIntercontinental Cooperative ITP Study Group
Thomas Kühne

Part IV. Translation from Polyclonal to Monoclonal Antibody Treatment

20. Therapeutic Monoclonal Antibodies as Immunomodulators and Anti-Cancer Agents: Development, Evidence of Efficacy, Mechanisms of Actions, Adverse Effects
Tim Niehues

21. Monoclonal Anti-CD20 (B-Cell) Antibody and Autoimmune Diseases
Bertrand Godeau

Keywords: Medicine & Public Health, Hematology, Immunology, Oncology