Garcia-Reyero, Natàlia
A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment
1. Advancing Adverse Outcome Pathways for Risk Assessment
Natàlia Garcia-Reyero, Cheryl A. Murphy
2. Use of High-Throughput and Computational Approaches for Endocrine Pathway Screening
Patience Browne, Warren M. Casey, David J. Dix
3. Cell-Free Assays in Environmental Toxicology
Adeline Arini, Krittika Mittal, Niladri Basu
4. The Fish Embryo as a Model for AOP Development
Lucia Vergauwen, Steven Cruchten, Dries Knapen
5. Invertebrate Model Species in AOP Development
Geoff Hodges, Steve Gutsell, Nadine Taylor, Erica Brockmeier, Emma Butler, Cecilie Rendal, John Colbourne
6. Non-model Species in Ecological Risk Assessment
Markus Hecker
7. Green Algae and Networks for Adverse Outcome Pathways
Anze Zupanic, Smitha Pillai, Diana Coman Schmid, Kristin Schirmer
8. Neurobehavioral Analysis Methods for Adverse Outcome Pathway (AOP) Models and Risk Assessment
Francisco X. Mora-Zamorano, Jeremy K. Larson, Michael J. Carvan
9. The Application of Omics Data to the Development of AOPs
Mary T. McBride
10. Use of Genetic Manipulation for Evaluating and Understanding Adverse Outcome Pathways
Christopher Warner, Natàlia Garcia-Reyero, Edward Perkins
11. Considering Epigenetics in Adverse Outcome Pathways
Kristine L. Willett
12. Tiered Approaches to Incorporate the Adverse Outcome Pathway Framework into Chemical-Specific Risk-Based Decision Making
Jeremy Leonard, Shannon Bell, Noffisat Oki, Mark Nelms, Yu-Mei Tan, Stephen Edwards
13. The Development of Quantitative AOPs
Irvin R. Schultz, Karen H. Watanabe
14. Linking Adverse Outcome Pathways to Dynamic Energy Budgets: A Conceptual Model
Cheryl A. Murphy, Roger M. Nisbet, Philipp Antczak, Natàlia Garcia-Reyero, Andre Gergs, Konstadia Lika, Teresa Mathews, Erik B. Muller, Diane Nacci, Angela Peace, Christopher H. Remien, Irvin R. Schultz, Karen H. Watanabe
15. Weight of Evidence Frameworks in Evaluation of Adverse Outcome Pathways
Taylor Rycroft, Olivia Massey, Christy M. Foran, Igor Linkov
16. Using a Vitellogenesis Model to Link in vitro Neurochemical Effects of Pulp and Paper Mill Effluents to Adverse Reproductive Outcomes in Fish
Brandon M. Armstrong, Cheryl A. Murphy, Niladri Basu
17. Use of Adverse Outcome Pathways in Human Risk Assessment and Toxicology
Catherine Willett, Suzanne Fitzpatrick, Bette Meek, Carl Westmoreland
18. Use and Acceptance of AOPs for Regulatory Applications
Clemens Wittwehr
19. The Future of Adverse Outcome Pathways: Analyzing their Social Context
Kevin C. Elliott, Cheryl A. Murphy, Natàlia Garcia-Reyero
Keywords: Life Sciences, Systems Biology, Pharmacology/Toxicology
- Editor
- Garcia-Reyero, Natàlia
- Murphy, Cheryl A.
- Publisher
- Springer
- Publication year
- 2018
- Language
- en
- Edition
- 1
- Page amount
- 14 pages
- Category
- Natural Sciences
- Format
- Ebook
- eISBN (PDF)
- 9783319660844
- Printed ISBN
- 978-3-319-66082-0