Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist

Part I. Introduction, History and the Basic Principles of Pediatric Hematopoietic Stem Cell Transplantation (HSCT)

1. Introduction
Valerie I. Brown

2. Historical Overview of Pediatric HSCT
Valerie I. Brown

3. Brief Introduction to the Basic Scientific Principles of Hematopoietic Stem Cell Transplantation (HSCT)
Valerie I. Brown

Part II. Topics Related to the Pre- HSCT Period

4. Pretransplantation: Indications and Timing
Alicia McFarren, Michael A. Pulsipher

5. Spotlight on Minimal Residual Disease (MRD): Impact of MRD on HSCT Outcomes for Pediatric Leukemia
Hisham Abdel-Azim, Michael A. Pulsipher

6. HSCT Recipient Pretransplantation Evaluation
Carrie Eichelberger, Valerie I. Brown

7. How to Select a Donor and Hematopoietic Stem Cell Source: Related Versus Unrelated Donors for Allogeneic HSCT
Malika Kapadia, Robert Greiner

8. Donor Evaluation, Selection and Hematopoietic Stem Cell Mobilization, Procurement, and Manipulation
William Ferguson, Aleksandar Babic

9. Preparing the Patient for HSCT: Conditioning Regimens and Their Scientific Rationale
Carrie-Lynn Kitko, Katie Gatwood, James Connelly

Part III. The Peri- HSCT Period: Pre-Engraftment (Days 0–30) and Early Post- HSCT (Days 30–100) Periods

10. Engraftment and Chimerism
Valerie I. Brown

11. Graft Failure
Valerie I. Brown

12. Engraftment Syndrome and Associated Cytokine Storm and Capillary Leak Syndrome
Mala K. Talekar, Jason L. Freedman

13. Nutrition in the Peri-HSCT Period
Arun Gurunathan, Judy Bailer, Jason L. Freedman

14. Mucositis and Pain in the Peri-HSCT Period
Arun Gurunathan, Neil S. Patel, Jason L. Freedman

15. Hepatotoxicity in the Peri-HSCT Period
Valerie I. Brown

16. Renal Toxicities in the Peri-HSCT Period
Malika Kapadia, Terry Wikle Shapiro, Robert Greiner

17. Infectious Complications and HSCT
Karen L. Bride, Ellen Levy, Anne Wohlschlaeger, Jason L. Freedman

18. Acute Graft-Versus-Host Disease: Diagnosis, Prophylaxis, and Treatment
Karen L. Bride, Neil S. Patel, Jason L. Freedman

Part IV. The Late Post- HSCT Period (> 100 Days)

19. Chronic GvHD
Terry Wikle Shapiro, Malika Kapadia

20. Hematologic Complications Associated with HSCT
Mala K. Talekar, Timothy Olson

21. Pulmonary Complications Associated with HSCT
Malika Kapadia, Terry Wikle Shapiro

22. Renal Complications Associated with HSCT
Lena E. Winestone, Alix E. Seif, Benjamin L. Laskin

23. Cardiac Complications Associated with HSCT
Valerie I. Brown

24. Neurologic and Sensory Complications Associated with HSCT
Valerie I. Brown

25. HSCT-Associated Complications of the Skin, Hair, and Nails
Valerie I. Brown

Part V. Life After HSCT

26. Immune Reconstitution After Hematopoietic Stem Cell Transplantation
Mala K. Talekar, Timothy Olson

27. Life After HSCT: Survivorship and Long-Term Issues
Smita Dandekar

Part VI. Pharmacologic-Related Issues of Pediatric HSCT

28. Medications Commonly Used in Pediatric HSCT
Kevin M. Mulieri, Ashley Teusink-Cross, JoEllen Weilnau, Krisoula Spatz, Katie S. Gatwood

Keywords: Medicine & Public Health, Hematology, Oncology