Mechanisms of Vascular Defects in Diabetes Mellitus

Part I. Introduction

1. The Global Burden of Diabetes and Its Vascular Complications
Viswanathan Mohan, Rajendra Pradeepa

Part II. Pathogenesis

2. Genetic Basis for Increased Risk for Vascular Diseases in Diabetes
Dwaipayan Bharadwaj, Anjali Singh

3. Vascular Remodeling in Diabetes Mellitus
Srikanth Vallurupalli, Jawahar L. Mehta

4. Pathogenesis of the Plaque Vulnerability in Diabetes Mellitus
Vikrant Rai, Devendra K. Agrawal

5. Endothelial Dysfunction in Diabetes
Shivam Chandel, Rakesh Kumar Tiwari, Madhulika Dixit

6. Smooth Muscle Cells in Diabetes Mellitus
Uma Nahar Saikia, Suvradeep Mitra

7. Monocyte Factors in Pathogenesis of Vascular Lesions in Diabetes
Surya Ramachandran, Radhakrishna M. Pillai, C. C. Kartha

8. Endothelial Progenitor Cell Dysfunction in the Pathogenesis of Vascular Complications of Diabetes
Nicoleta Alexandru, Irina Titorencu, Sabina Frunzã, Emma Weiss, Elisabeta Bãdilã, Adriana Georgescu

9. Pathogenetic Mechanisms in Diabetic Retinopathy: From Molecules to Cells to Tissues
Saumik Biswas, Subrata Chakrabarti

10. Perspectives on the Vascular Pathogenesis of Diabetic Neuropathy
Anita Mahadevan, Shankar S. Krishna

Part III. Molecular Mechanisms

11. The Renin Angiotensin System and Diabetes
Ana Cristina Simões e Silva, Rodrigo Novaes Ferreira, Aline Silva Miranda

12. Adipokines and Vascular Disease in Diabetes
Camille M. Balarini

13. G-Proteins in Vascular Complications of Diabetes
Madhu B. Anand-Srivastava

14. Histone Deacetylases in Vascular Pathophysiology: Regulation by Vasoactive Peptides and Growth Factors
Paulina Pietruczuk, Ashok K. Srivastava

15. Role of Non-coding RNAs in Vascular Complications of Diabetes Mellitus
Sumi Surendran, C. C. Kartha

Part IV. Hemostatic Factors

16. Diabetes as a Prothrombotic State
Kanjaksha Ghosh

17. Mechanisms of Hypercoagulation and Aberrant Clot Lyses in Type 2 Diabetes
Etheresia Pretorius

18. Platelet Dysfunction in Type-2 Diabetes Mellitus
Gundu H. R. Rao

Part V. Metabolic Factors

19. Advanced Glycation End Products (AGEs) in Diabetic Complications
Shweta Bhat, Sheon Mary, Ashok P. Giri, Mahesh J. Kulkarni

20. Atherogenic Dyslipoproteinemia in Type 2 Diabetes Mellitus
G Arungovind, A. S Kamalanathan, Krishnan Venkataraman

21. Vascular Remodeling: Homocysteine and Diabetes
Pankaj Chaturvedi

Part VI. Pharmacological Therapies

22. Mechanisms of Action of Drugs for Treating Endothelial Dysfunction in Diabetes Mellitus
Hina L. Nizami, Sanjay K. Banerjee

23. Beneficial Effects of Inorganic Nitrate/Nitrite on Vascular Function and Blood Pressure in Diabetes
Zahra Bahadoran, Parvin Mirmiran, Asghar Ghasemi

24. Myeloperoxidase (MPO): Do We Need Inhibitors?
Rajagopal Desikan, Chandrakala Aluganti Narasimhulu, Bobby Khan, Sanjay Rajagopalan, Sampath Parthasarathy

Keywords: Life Sciences, Cell Biology, Diabetes