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Giovanni, Giuseppe Di

G-Protein-Coupled Receptor Dimers

Giovanni, Giuseppe Di - G-Protein-Coupled Receptor Dimers, ebook

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ISBN: 9783319601748
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Table of contents

Part I. Introduction

1. Historical Perspectives: From Monomers to Dimers and Beyond, an Exciting Journey in the World of G Protein-Coupled Receptors
Mario Rossi, Roberto Maggio, Irene Fasciani, Marco Scarselli

2. The Use of Spatial Intensity Distribution Analysis to Examine G Protein-Coupled Receptor Oligomerization
Richard J. Ward, Sara Marsango, John D. Pediani, Graeme Milligan

3. Advanced Microscopy Techniques
Valerica Raicu, William F. Schmidt

Part II. Receptors

4. Class A GPCR: Light Sensing G Protein-Coupled Receptor – Focus on Rhodopsin Dimer
Beata Jastrzebska

5. Extreme Vetting of Dopamine Receptor Oligomerization
Wesley B. Asher, Signe Mathiasen, Michael D. Holsey, Steven G. Grinnell, Nevin A. Lambert, Jonathan A. Javitch

6. Class A GPCR: Serotonin Receptors
Ellinor Grinde, Katharine Herrick-Davis

7. Class A GPCRs: Cannabinoid and Opioid Receptor Heteromers
Salvador Sierra, Ivone Gomes, Lakshmi A. Devi

8. Class A GPCR: Di/Oligomerization of Glycoprotein Hormone Receptors
Aylin C. Hanyaloglu, F. Fanelli, K. C. Jonas

9. Chemokine Receptor Oligomerization to Tweak Chemotactic Responses
Henry F. Vischer

10. Secretin Receptor Dimerization. Prototypic of Class B GPCR Behavior
Kaleeckal G. Harikumar, Laurence J. Miller

11. Class B GPCR: Receptors and RAMPs
Joseph J. Gingell, Christopher S. Walker, Debbie L. Hay

12. Class C GPCR: Obligatory Heterodimerization of GABAB Receptor
Qing R. Fan, William Y. Guo, Yong Geng, Marisa G. Evelyn

13. Class C GPCRs: Metabotropic Glutamate Receptors
Veronika Hlaváčková, Laurent Prézeau, Jean-Philippe Pin, Jaroslav Blahos

Part III. Assembly and Trafficking

14. The Monomer/Homodimer Equilibrium of G Protein-Coupled Receptors: Formation in the Secretory Pathway and Potential Functional Significance
Arthur Gibert, Martin Lehmann, Burkhard Wiesner, Ralf Schülein

15. Probing Self-Assembly of G Protein-Coupled Receptor Oligomers in Membranes Using Molecular Dynamics Modeling and Experimental Approaches
Thomas P. Sakmar, Xavier Periole, Thomas Huber

16. Interaction of Membrane Cholesterol with GPCRs: Implications in Receptor Oligomerization
Durba Sengupta, G. Aditya Kumar, Amitabha Chattopadhyay

Part IV. Physiology and Therapeutic Potential

17. Allosterism Within GPCR Oligomers: Back to Symmetry
Sergi Ferré

18. Understanding the Physiological Significance of GPCR Dimers and Oligomers
Rory Sleno, Dominic Devost, Terence E. Hébert

19. Heteromers Form Novel Signaling Complexes
Peter J. McCormick, Joaquin Botta

20. Heteroreceptor Complexes Implicated in Parkinson’s Disease
Dasiel O. Borroto-Escuela, Manuel Narváez, Gemma Navarro, Rafael Franco, Kjell Fuxe

Keywords: Biomedicine, Neurosciences

Editor
 
 
Publisher
Springer
Publication year
2017
Language
en
Edition
1
Series
The Receptors
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9783319601748
Printed ISBN
978-3-319-60172-4

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