DNA and Histone Methylation as Cancer Targets

1. DNA and Histone Methylation in Epigenetics
Hengbin Wang, Jinrong Min, Trygve Tollefsbol

Part I. DNA Methylation and Cancer

2. The Molecular Basis of DNA Methylation
Isao Suetake, Mikio Watanebe, Kohei Takeshita, Saori Takahashi, Peter Carlton

3. The Molecular Basis of DNA Demethylation
Miao Shi, Li Shen

4. DNA Methylation Changes in Cancer
John P. Thomson, Richard R. Meehan

5. Misregulation of DNA Methylation Regulators in Cancer
Joyce J. Thompson, Keith D. Robertson

Part II. Histone Methylation and Cancer

6. The Molecular Basis of Histone Methylation
Lidong Sun, Jia Fang

7. The Molecular Basis of Histone Demethylation
John R. Horton, Molly Gale, Qin Yan, Xiaodong Cheng

8. Misregulation of Histone Methylation Regulators in Cancer
Wen Fong Ooi, Xiaosai Yao, Patrick Tan, Bin Tean Teh

9. Other Histone Modifications
Hiroaki Kato

Part III. DNA and Histone Methylation-Related Events Underlying Cancer

10. DNA Methylation and Dysregulation of miRNA in Cancer
Akira Kurozumi, Yusuke Goto, Atsushi Okato, Naohiko Seki

11. Genomic Imprinting Syndromes and Cancer
Ken Higashimoto, Keiichiro Joh, Hidenobu Soejima

Part IV. DNA and Histone Methylation in Particular Types of Cancer

12. DNA and Histone Methylation in Brain Cancer
Sung-Hun Lee, Young Zoon Kim

13. DNA and Histone Methylation in Gastric Cancer
Keisuke Matsusaka, Atsushi Kaneda

14. DNA and Histone Methylation in Hematopoietic Malignancy
Kimihito Cojin Kawabata, Toshio Kitamura

15. DNA and Histone Methylation in Lung Cancer
Sophia Mastoraki, Evi Lianidou

16. DNA and Histone Methylation in Liver Cancer
Eri Arai, Takuya Yotani, Yae Kanai

17. DNA and Histone Methylation in Colon Cancer
Hiromu Suzuki, Eiichiro Yamamoto, Hiroshi Nakase, Tamotsu Sugai

18. DNA and Histone Methylation in Prostate Cancer
Kexin Xu

Part V. DNA and Histone Modifications in Diagnosis and Therapy of Cancer

19. DNA and Histone Modifications in Cancer Diagnosis
Masaki Kinehara, Yuki Yamamoto, Yoshitomo Shiroma, Mariko Ikuo, Akira Shimamoto, Hidetoshi Tahara

20. DNA and Histone Modifications in Cancer Therapy
Takayoshi Suzuki

Part VI. Future Directions

21. Future Perspective of DNA and Histone Methylation as Cancer Targets
Hideyuki Takeshima, Toshikazu Ushijima

Keywords: Biomedicine, Cancer Research