Bhattacharya, Sanjoy K.

Protein Deimination in Human Health and Disease

Bhattacharya, Sanjoy K. - Protein Deimination in Human Health and Disease, ebook


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Table of contents

1. A History of Deimination Research in Japan: The Founding Fathers
Hidenari Takahara

2. Aspects of Peptidylarginine Deiminase Regulation that May Predispose to Autoreactivity Against Citrullinated Proteins
Indira Neeli, Marko Radic

3. Structures and Functions of Peptidylarginine Deiminases
Masaki Unno, Kenji Kizawa, Hidenari Takahara

4. The Use of Genetically Engineered Mice to Study PAD Biology and Pathology
Chinatsu Mukai, Brooke A. Marks, Scott A. Coonrod

5. PAD Activation in Arthritis
Dres Damgaard, Ger J. M. Pruijn

6. Rheumatoid Arthritis: Transition from Systemic Autoimmunity to Joint Inflammation and Bone Loss
Bence Rethi, Akilan Krishnamurthy, Anca I. Catrina

Porphyromonas gingivalis Peptidyl Arginine Deiminase: A Unique Bacterial PAD with Implications for Periodontal Disease and Rheumatoid Arthritis
Katarzyna Gawron, Anna Montgomery, Katarzyna Łazarz-Bartyzel, Grzegorz Bereta, Maria Chomyszyn-Gajewska, Patrick Venables, Jan Potempa

8. Citrullination and Neutrophil Extracellular Traps
Nishant Dwivedi, Hui-Hsin Chang, I-Cheng Ho

9. Citrullination and Autophagy
Guido Valesini, Tania Colasanti, Cristiano Alessandri, Michele Bombardieri, Fabrizio Conti, Maurizio Sorice

10. Antigen Deimination in Human Type 1 Diabetes and Nonobese Diabetic Mice
Hai Nguyen, Eddie A. James

11. Citrullinated Autoantigen Targets as Markers of Extra-Articular Disease in Rheumatoid Arthritis
Vinitha Ganesan, Dana P. Ascherman

12. The Significance of Myofilament Protein Citrullination in Heart Failure: Citrullination in Cardiovascular Diseases
J. Fert-Bober, E. L. Crowgey, J. Sokolove, J. T. Giles, J. M. Bathon, J. E. Eyk

13. Protein Deimination in Protein Misfolding Disorders: Modeled in Human Induced Pluripotent Stem Cells (iPSCs)
Sigrun Lange, Selina Wray, Mike Devine, Mar Matarin, John Hardy

14. Protein Deimination in Aging and Age-Related Diseases with Ocular Manifestations
Di Ding, Mabel Enriquez-Algeciras, Sanjoy K. Bhattacharya, Vera L. Bonilha

15. Chemical Modification and Mass Spectrometric Approaches for Detection of Brain Protein Deimination
Mabel Enriquez-Algeciras, Di Ding, Dana P. Ascherman, Sanjoy K. Bhattacharya

16. Citrullination Following Traumatic Brain Injury: A Mechanism for Ongoing Pathology Through Protein Modification
Rachel C. Lazarus, John E. Buonora, Alaa Kamnaksh, Michael N. Flora, James G. Freedy, Gay R. Holstein, Giorgio P. Martinelli, David M. Jacobowitz, Denes Agoston, Gregory P. Mueller

17. Update on Deimination in Alzheimer’s Disease
Yoshitaka Kondo, Eun-Kyoung Choi, Yong-Sun Kim, Akihito Ishigami

18. Deimination in Multiple Sclerosis: The Bad, the Good, and the Ugly
William R. Meador, John R. Rinker, Anthony P. Nicholas

19. Turning White Matter “Inside-Out” by Hyper-deimination of Myelin Basic Protein (MBP)
George Harauz

20. The Significance of Deiminated GFAP in Neurodegenerative Diseases with Special Emphasis on Alexander Disease
Michael Brenner, Anthony P. Nicholas

21. Treatment of Prostate Cancer Using Deimination Antagonists and Microvesicle Technology
Sigrun Lange, Sharad Kholia, Uchini S. Kosgodage, Jameel M. Inal

22. Citrullination in Inflammatory-Driven Carcinogenesis of the Colon
Erin E. Witalison, Lorne J. Hofseth

23. Development of the Protein Arginine Deiminase (PAD) Inhibitors
Aaron Muth, Paul R. Thompson

Keywords: Biomedicine, Neurosciences, Immunology, Protein Science

Publication year
2nd ed. 2017
Page amount
9 pages
Medicine, Health Care, Mode
Printed ISBN

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