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Samadfam, Rana

Bone Toxicology

Samadfam, Rana - Bone Toxicology, ebook

230,65€

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ISBN: 9783319561929
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Table of contents

Part I. Bone Toxicology in Preclinical Drug Testing

1. Introduction and Considerations in Bone Toxicology
Susan Y. Smith, Nancy Doyle, Melanie Felx

2. Bone Physiology and Biology
Jürg Andreas Gasser, Michaela Kneissel

3. Specific Considerations for Bone Evaluations for Pediatric Therapeutics
Keith Robinson

4. Animal Models in Bone Research
Donald B. Kimmel

Part II. Methods in Bone Research

5. Biochemical Markers of Bone Turnover
Susan Y. Smith, Rana Samadfam

6. Skeletal Imaging
Aurore Varela

7. Biomechanics
Angela S. P. Lin, Gabrielle Boyd, Aurore Varela, Robert E. Guldberg

8. Application of Histopathology and Bone Histomorphometry for Understanding Test Article-Related Bone Changes and Assessing Potential Bone Liabilities
Reinhold G. Erben, Jacquelin Jolette, Luc Chouinard, Rogely Boyce

Part III. Bone as an Endocrine Organ

9. Bone and Muscle
Chenglin Mo, Zhiying Wang, Lynda Bonewald, Marco Brotto

10. Pituitary Hormone-Driven Mechanism for Skeletal Loss
Tony Yuen, Li Sun, Wahid Abu-Amer, Peng Liu, Terry F. Davies, Harry C. Blair, Maria New, Alberta Zallone, Mone Zaidi

11. Kidney–Bone: Interaction
Olena V. Andrukhova, Reinhold G. Erben

12. Bone and the Immune System
M. Neale Weitzmann

13. Bone and the Central Nervous System
Rishikesh N. Kulkarni, Paul A. Baldock

14. Intestinal Microbiota and Bone Health: The Role of Prebiotics, Probiotics, and Diet
Fraser L. Collins, Soon Mi Kim, Laura R. McCabe, Connie M. Weaver

15. Bone and Energy Metabolism
Clifford J. Rosen

Keywords: Biomedicine, Pharmacology/Toxicology, Pharmaceutical Sciences/Technology, Animal Models

Editor
 
 
Publisher
Springer
Publication year
2017
Language
en
Edition
1
Series
Molecular and Integrative Toxicology
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9783319561929
Printed ISBN
978-3-319-56190-5

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