Nikolaev, Viacheslav

Microdomains in the Cardiovascular System

Nikolaev, Viacheslav - Microdomains in the Cardiovascular System, ebook


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ISBN: 9783319545790
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Table of contents

Part I. Cyclic Nucleotide Microdomains

1. Receptor-Cyclic Nucleotide Microdomains in the Heart
Nadja I. Bork, Viacheslav O. Nikolaev

2. Membrane Microdomains and cAMP Compartmentation in Cardiac Myocytes
Shailesh R. Agarwal, Rennolds S. Ostrom, Robert D. Harvey

3. Function to Failure: Compartmentalization of Cardiomyocyte Signaling by A-Kinase-Anchoring Proteins
John M. Redden, Kimberly L. Dodge-Kafka, Michael S. Kapiloff

4. Pharmacological Approaches for Delineating Functions of AKAP-Based Signalling Complexes and Finding Therapeutic Targets
Katharina Schrade, Enno Klussmann

5. Chatting Second Messengers: PIP3 and cAMP
Alessandra Ghigo, Flora Pirozzi, Mingchuan Li, Emilio Hirsch

6. Cyclic Nucleotide Phosphodiesterases and Compartmentation in Normal and Diseased Heart
Ibrahim Bedioune, Pierre Bobin, Jérôme Leroy, Rodolphe Fischmeister, Grégoire Vandecasteele

7. cAMP Compartmentalisation and Hypertrophy of the Heart: ‘Good’ Pools of cAMP and ‘Bad’ Pools of cAMP Coexist in the Same Cardiac Myocyte
Anna Zoccarato, Manuela Zaccolo

8. Subcellular Targeting of PDE4 in Cardiac Myocytes and Generation of Signaling Compartments
Marco Conti

9. Cardiac cAMP Microdomains and Their Modulation Using Disruptor Peptides
Lauren Wills, Bracy A. Fertig, George S. Baillie

10. Computational Modeling of Cyclic Nucleotide Signaling Mechanisms in Cardiac Myocytes
Claire Y. Zhao

11. Signalling Microdomains: The Beta-3 Adrenergic Receptor/NOS Signalosome
J. Hammond, J.-L. Balligand

12. Compartmentation of Natriuretic Peptide Signalling in Cardiac Myocytes: Effects on Cardiac Contractility and Hypertrophy
Lise Román Moltzau, Silja Meier, Kjetil Wessel Andressen, Finn Olav Levy

13. Cyclic GMP/Protein Kinase Localized Signaling and Disease Implications
Brian Leei Lin, David A. Kass, Dong I. Lee

Part II. Calcium Microdomains

14. Distribution and Regulation of L-Type Ca2+ Channels in Cardiomyocyte Microdomains
Alexey V. Glukhov, Anamika Bhargava, Julia Gorelik

15. The Role of Local Ca2+ Release for Ca2+ Alternans and SR-Ca2+ Leak
Karin P. Hammer, Lars S. Maier

16. The Control of Sub-plasma Membrane Calcium Signalling by the Plasma Membrane Calcium ATPase Pump PMCA4
Nicholas Stafford, Ludwig Neyses, Delvac Oceandy

17. Calcium Microdomains in Cardiac Cells
A. M. Gómez, T. R. R. Mesquita, J. J. Mercadier, J. L. Álvarez, J. P. Benitah

Keywords: Biomedicine, Human Physiology, Cell Biology, Cardiology

Publication year
Cardiac and Vascular Biology
Page amount
8 pages
Medicine, Health Care, Mode
Printed ISBN

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