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Guest, Paul C.

Proteomic Methods in Neuropsychiatric Research

Guest, Paul C. - Proteomic Methods in Neuropsychiatric Research, ebook

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ISBN: 9783319524795
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Table of contents

Part I. Reviews

1. Application of Proteomic Techniques for Improved Stratification and Treatment of Schizophrenia Patients
Johann Steiner, Paul C. Guest, Daniel Martins-de-Souza

2. Multiplexing Biomarker Methods, Proteomics and Considerations for Alzheimer’s Disease
Renã A. S. Robinson, Bushra Amin, Paul C. Guest

3. What Have Proteomic Studies Taught Us About Novel Drug Targets in Autism?
Paul C. Guest, Daniel Martins-de-Souza

4. Application of Proteomic Approaches to Accelerate Drug Development for Psychiatric Disorders
Hassan Rahmoune, Daniel Martins-de-Souza, Paul C. Guest

5. Proteomic Biomarker Identification in Cerebrospinal Fluid for Leptomeningeal Metastases with Neurological Complications
Norma Galicia, Paula Díez, Rosa M. Dégano, Paul C. Guest, Nieves Ibarrola, Manuel Fuentes

6. Connecting Brain Proteomics with Behavioural Neuroscience in Translational Animal Models of Neuropsychiatric Disorders
Zoltán Sarnyai, Paul C. Guest

7. LC-MSE for Qualitative and Quantitative Proteomic Studies of Psychiatric Disorders
Mariana Fioramonte, Paul C. Guest, Daniel Martins-de-Souza

8. The Utility of Multiplex Assays for Identification of Proteomic Signatures in Psychiatry
Junfang Chen, Paul C. Guest, Emanuel Schwarz

Part II. Protocols

9. Blood Sampling and Preparation Procedures for Proteomic Biomarker Studies of Psychiatric Disorders
Paul C. Guest, Hassan Rahmoune

10. Multiplex Immunoassay Profiling of Serum in Psychiatric Disorders
Laurie Stephen, Emanuel Schwarz, Paul C. Guest

11. Sequential Immunoprecipitation of Secretory Vesicle Proteins from Biosynthetically Labelled Cells
Paul C. Guest

12. 2D Gel Electrophoresis of Insulin Secretory Granule Proteins from Biosynthetically Labelled Pancreatic Islets
Paul C. Guest

13. Two-Dimensional Gel Electrophoresis: A Reference Protocol
Veronica M. Saia-Cereda, Adriano Aquino, Paul C. Guest, Daniel Martins-de-Souza

14. A Two-Dimensional Difference Gel Electrophoresis (2D-DIGE) Protocol for Studies of Neural Precursor Cells
Paul C. Guest

15. Identifying Biomarker Candidates in the Blood Plasma or Serum Proteome
Sheila Garcia, Licia C. Silva-Costa, Guilherme Reis-de-Oliveira, Paul C. Guest, Paulo A. Baldasso, Juliana S. Cassoli, Daniel Martins-de-Souza

16. Selective Reaction Monitoring Mass Spectrometry for Quantitation of Glycolytic Enzymes in Postmortem Brain Samples
Guilherme Lanfredi, Guiherme Reis-de-Oliveira, Veronica M. Saia-Cereda, Paul C. Guest, Daniel Martins-de-Souza, Vitor M. Faça

17. A Selected Reaction Monitoring Mass Spectrometry Protocol for Validation of Proteomic Biomarker Candidates in Studies of Psychiatric Disorders
Guilherme Reis-de-Oliveira, Sheila Garcia, Paul C. Guest, Juliana S. Cassoli, Daniel Martins-de-Souza

18. Application of iTRAQ Shotgun Proteomics for Measurement of Brain Proteins in Studies of Psychiatric Disorders
Erika Velásquez Núñez, Paul C. Guest, Daniel Martins-de-Souza, Gilberto Barbosa Domont, Fábio César Sousa Nogueira

19. Co-immunoprecipitation for Deciphering Protein Interactomes
Bradley J. Smith, Juliana S. Cassoli, Paul C. Guest, Daniel Martins-de-Souza

20. Sequential Co-immunoprecipitation and Immunoblot Approach to Determine Oligomerisation of G-Protein-Coupled Receptors
Paul C. Guest

21. A Clinical Study Protocol to Identify Serum Biomarkers Predictive of Response to Antipsychotics in Schizophrenia Patients
Johann Steiner, Paul C. Guest

22. A Protocol for Producing the Maternal Low-Protein Rat Model: A Tool for Preclinical Proteomic Studies
Dan Ma, Susan E. Ozanne, Paul C. Guest

23. Generation of the Acute Phencyclidine Rat Model for Proteomic Studies of Schizophrenia
Dan Ma, Paul C. Guest

24. A Protocol for Generation of a Corticosterone Model of Psychiatric Disorders
Paul C. Guest

25. MK-801-Treated Oligodendrocytes as a Cellular Model to Study Schizophrenia
Caroline Brandão-Teles, Daniel Martins-de-Souza, Paul C. Guest, Juliana S. Cassoli

26. Combining Patient-Reprogrammed Neural Cells and Proteomics as a Model to Study Psychiatric Disorders
Giuliana S. Zuccoli, Daniel Martins-de-Souza, Paul C. Guest, Stevens K. Rehen, Juliana Minardi Nascimento

27. SILAC Mass Spectrometry Profiling: A Psychiatric Disorder Perspective
Daniella Duque-Guimarães, Thomas Prates Ong, Juliana Almeida-Faria, Paul C. Guest, Susan E. Ozanne

28. Preparation of Peripheral Blood Mononuclear Cells (PBMCs) as a Model for Proteomic Studies of Psychiatric Disorders
Hassan Rahmoune, Paul C. Guest

29. Proteomic Profiling of Skin Fibroblasts as a Model of Schizophrenia
Lan Wang, Hassan Rahmoune, Paul C. Guest

30. Proteomic Profiling of the Pituitary Gland in Studies of Psychiatric Disorders
Divya Krishnamurthy, Hassan Rahmoune, Paul C. Guest

31. Development of an Assay for Measuring Proprotein-Conversion Activity on a Multiplex Magnetic Bead-Based Array Platform
Paul C. Guest, Divya Krishnamurthy, Hassan Rahmoune

32. Phenotyping Multiple Subsets of Immune Cells In Situ in Formalin-Fixed, Paraffin-Embedded Tissue Sections
James R. Mansfield, Paul C. Guest, Jared Burks

33. Lab-on-a-Chip Proteomic Assays for Psychiatric Disorders
Harald Peter, Julia Wienke, Paul C. Guest, Nikitas Bistolas, Frank F. Bier

34. Development of a User-Friendly App for Testing Blood Coagulation Status in Schizophrenia Patients
Johannes Vegt, Paul C. Guest

Part III. Future Perspectives

35. Proteomic Approaches to Enable Point-of-Care Testing and Personalized Medicine for Psychiatric Disorders
Francesca L. Guest, Paul C. Guest

Keywords: Life Sciences, Proteomics, Gene Expression, Gene Therapy

Editor
Publisher
Springer
Publication year
2017
Language
en
Edition
1
Series
Advances in Experimental Medicine and Biology
Category
Natural Sciences
Format
Ebook
eISBN (PDF)
9783319524795
Printed ISBN
978-3-319-52478-8

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