Neuropharmacology of New Psychoactive Substances (NPS)

1. The Growing Problem of New Psychoactive Substances (NPS)
Bertha K. Madras

2. Structure-Activity Relationships of Synthetic Cathinones
Richard A. Glennon, Małgorzata Dukat

3. Interactions of Cathinone NPS with Human Transporters and Receptors in Transfected Cells
Linda D. Simmler, Matthias E. Liechti

4. Electrophysiological Actions of Synthetic Cathinones on Monoamine Transporters
Ernesto Solis

5. Neuropharmacology of 3,4-Methylenedioxypyrovalerone (MDPV), Its Metabolites, and Related Analogs
Michael H. Baumann, Mohammad O. Bukhari, Kurt R. Lehner, Sebastien Anizan, Kenner C. Rice, Marta Concheiro, Marilyn A. Huestis

6. Decoding the Structure of Abuse Potential for New Psychoactive Substances: Structure–Activity Relationships for Abuse-Related Effects of 4-Substituted Methcathinone Analogs
S. Stevens Negus, Matthew L. Banks

7. Reinforcing Effects of Cathinone NPS in the Intravenous Drug Self-Administration Paradigm
Lucas R. Watterson, M. Foster Olive

8. Predicting the Abuse Liability of Entactogen-Class, New and Emerging Psychoactive Substances via Preclinical Models of Drug Self-administration
Shawn M. Aarde, Michael A. Taffe

9. The Affective Properties of Synthetic Cathinones: Role of Reward and Aversion in Their Abuse
Heather E. King, Anthony L. Riley

10. MDMA, Methylone, and MDPV: Drug-Induced Brain Hyperthermia and Its Modulation by Activity State and Environment
Eugene A. Kiyatkin, Suelynn E. Ren

11. Neurotoxicology of Synthetic Cathinone Analogs
Mariana Angoa-Pérez, John H. Anneken, Donald M. Kuhn

12. Combination Chemistry: Structure–Activity Relationships of Novel Psychoactive Cannabinoids
Jenny L. Wiley, Julie A. Marusich, Brian F. Thomas

13. Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites
Sherrica Tai, William E. Fantegrossi

14. Tripping with Synthetic Cannabinoids (“Spice”): Anecdotal and Experimental Observations in Animals and Man
Torbjörn U. C. Järbe, Jimit Girish Raghav

15. Pharmacology and Toxicology of N-Benzylphenethylamine (“NBOMe”) Hallucinogens
Adam L. Halberstadt

16. Clinical Pharmacology of the Synthetic Cathinone Mephedrone
Esther Papaseit, José Moltó, Robert Muga, Marta Torrens, Rafael Torre, Magí Farré

17. Application of a Combined Approach to Identify New Psychoactive Street Drugs and Decipher Their Mechanisms at Monoamine Transporters
Felix P. Mayer, Anton Luf, Constanze Nagy, Marion Holy, Rainer Schmid, Michael Freissmuth, Harald H. Sitte

18. NPS: Medical Consequences Associated with Their Intake
Fabrizio Schifano, Laura Orsolini, Duccio Papanti, John Corkery

Keywords: Biomedicine, Neurosciences, Psychopharmacology, Pharmacology/Toxicology, Public Health