Pediatric Inflammatory Bowel Disease

Part I. Etiology and Pathogenesis

1. Genetics of Inflammatory Bowel Diseases
Christopher J. Cardinale, Hakon Hakonarson

2. The Intestinal Immune System During Homeostasis and Inflammatory Bowel Disease
David A. Hill, William A. Faubion

3. Cytokines and Inflammatory Bowel Disease
Edwin F. Zoeten, Ivan J. Fuss

4. The Gut Microbiota and Inflammatory Bowel Disease
Máire A. Conrad, Gary D. Wu, Judith R. Kelsen

5. Immune Dysregulation Associated with Very Early-Onset Inflammatory Bowel Disease
Judith Kelsen, Kathleen Sullivan

Part II. Epidemiology and Clinical Features

6. Epidemiology of Pediatric Inflammatory Bowel Disease
Shehzad A. Saeed, Subra Kugathasan

7. The Natural History of Crohn Disease in Children
Benjamin Sahn, James Markowitz

8. Natural History of Ulcerative Colitis in Children
Peter Townsend, Jeffrey S. Hyams

9. Natural History of Pediatric Indeterminate Colitis
Melissa A. Fernandes, Sofia Verstraete, Melvin B. Heyman

10. Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease
Shervin Rabizadeh, Maria Oliva-Hemker

11. Liver Disease in Pediatric Inflammatory Bowel Disease
Amanda Ricciuto, Binita M. Kamath

12. Growth Impairment in Pediatric Inflammatory Bowel Disease
Thomas D. Walters, Anne M. Griffiths

13. Inflammatory Bowel Diseases and Skeletal Health
Francisco Sylvester

14. Puberty and Pediatric-Onset Inflammatory Bowel Disease
Dianne Deplewski, Neera Gupta, Barbara S. Kirschner

15. Classification of Inflammatory Bowel Disease in Children
Mary E. Sherlock, Eric I. Benchimol

Part III. Diagnosis

16. The History and Physical Exam
Alka Goyal

17. Differential Diagnosis of Inflammatory Bowel Disease
Thierry Lamireau, Raphael Enaud

18. Laboratory Evaluation of Inflammatory Bowel Disease
Jennifer Strople, Benjamin D. Gold

19. Fecal Biomarkers in Inflammatory Bowel Disease
Jennifer Damman, K. T. Park

20. Radiologic Evaluation of Pediatric Inflammatory Bowel Disease
Stephen M. Druhan, Benedict C. Nwomeh

21. Endoscopy and Inflammatory Bowel Disease
Shishu Sharma, Krishnappa Venkatesh, Mike Thomson

22. The Pathology of Chronic Inflammatory Bowel Disease
Pierre Russo

23. Video Capsule Endoscopy in Inflammatory Bowel Disease
Ernest G. Seidman, Che Yung Chao, Ana Maria Sant’Anna

24. Bone Health in Pediatric Inflammatory Bowel Disease
Dale Lee, Edisio Semeao

Part IV. Medical Therapy

25. 5-Aminosalicylate Therapy
Michael Stephens, Michelle Gonzalez

26. Antibiotic Therapy
Lindsey Albenberg, Howard Kader, Adam Paul

27. Nutritional Management of Inflammatory Bowel Disease
Anthony R. Otley, Andrew S. Day, Mary Zachos

28. Probiotic Therapy
David R. Mack

29. Corticosteroids
Charles M. Samson, Johanna C. Escher

30. 6-Mercaptopurine Therapy
Carmen Cuffari

31. Methotrexate
Joel R. Rosh

32. Infliximab Therapy for Pediatric Crohn Disease and Ulcerative Colitis
Philip Minar, Dana MH. Dykes, Ana Catalina Arce-Clachar, Shehzad A. Saeed

33. Anti-TNF Biologic Therapies Other than Infliximab
Calen A. Steiner, Emily P. Whitfield, Jeremy Adler, Peter D. R. Higgins

34. Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease
Namita Singh, Marla C. Dubinsky

35. New Non-anti-TNF-α Biological Therapies for the Treatment of Inflammatory Bowel Disease
Farzana Rashid, Gary R. Lichtenstein

36. Medical Treatment of Perianal Crohn’s Disease Fistulae
Mark T. Osterman, Gary R. Lichtenstein

37. Treatment of Acute Severe Ulcerative Colitis
Jess L. Kaplan, Harland S. Winter

38. Dietary Therapies for Inflammatory Bowel Disease
Ronen Stein, Robert N. Baldassano

39. Complementary and Alternative Therapies
Jennifer Panganiban, Jessi Erlichman, Maria Mascarenhas

Part V. Surgical Considerations

40. Management of Intra-abdominal Complications of Inflammatory Bowel Disease
Elizabeth C. Maxwell, Peter Mattei, Andrew B. Grossman

41. Surgical Management of Crohn Disease in Children
Daniel Allmen

42. Surgical Treatment of Ulcerative Colitis
Peter Mattei

43. Postoperative Surveillance and Management of Crohn’s Disease
Arthur M. Barrie, Miguel Regueiro

44. Pouchitis After Ileal Pouch-Anal Anastomosis
Jacob Kurowski, Marsha Kay, Robert Wyllie

45. Enteral Feeding Devices and Ostomies
Judith J. Stellar

Part VI. Research

46. Clinical Indices for Pediatric Inflammatory Bowel Disease Research
Dan Turner, Oren Ledder

47. Clinical Trials (Clinical Perspective)
Salvatore Cucchiara, Marina Aloi

48. Clinical Trials (Industry/Regulatory Perspective)
Tara Altepeter, Kurt Brown, Aisha Peterson Johnson, Andrew E. Mulberg

Part VII. Special Considerations

49. Infectious Complications of Pediatric Inflammatory Bowel Disease
Monica I. Ardura, Sandra C. Kim

50. Psychological Aspects of Inflammatory Bowel Disease in Children and Adolescents
Bonney Reed-Knight, Laura M. Mackner, Wallace V. Crandall

51. Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease
Amy Grant, Anthony Otley

52. Irritable Bowel Syndrome and Functional GI Disorders in Inflammatory Bowel Disease
Khalil I. El-Chammas, Manu R. Sood

53. Inflammatory Bowel Disease in Pregnancy
Sunanda Kane

54. Immunizations in the Child with Inflammatory Bowel Disease
Athos Bousvaros, Ying Lu

55. Malignant Tumors Arising in Inflammatory Bowel Disease
Thomas A. Ullman, Rona Yaeger

56. Quality Improvement in Inflammatory Bowel Disease
Jeremy Adler, Richard B. Colletti, Wallace V. Crandall, Peter A. Margolis

57. Fostering Self-Management and Patient Activation
David Alain Wohl, Justin Vandergrift

58. Advocacy for Pediatric Patients with IBD
Janis Arnold, Athos Bousvaros

59. Legislative Advocacy
Sarah Buchanan

60. Transition from Pediatric to Adult Care
Stacy A. Kahn, Sandra C. Kim

Keywords: Medicine & Public Health, Gastroenterology