The Pathology of Cardiac Transplantation

Part I. Introduction

1. Cardiac Transplantation and the Contribution of Pathology
Margaret Burke, Luciano Potena

Part II. Prior to Cardiac Transplantation

2. Advanced End-Stage Heart Failure: Epidemiology and Management
John Parissis, Spyridon Katsanos, Sergei Pepoyan, Gerasimos Filippatos

3. Mechanical Circulatory Support in End-Stage Heart Failure: Bridge to Transplantation and Destination Therapy
Alexander Stepanenko, Evgenij Potapov, Volkmar Falk, Thomas Krabatsch

4. Clinical Indications for Heart Transplantation
Francesco Tona, Carlo Dal Lin

5. Pathologies Encountered in Explanted Native Hearts
Ornella Leone, Annalisa Angelini, Marny Fedrigo, Aryan Vink, Allard Wal

6. Pretransplant Endomyocardial Biopsy: When and Why
John P. Veinot

Part III. Heart Donation and Peritransplant Pathologies

7. Donor Selection Criteria: Clinical and Pathological Insights
Ornella Leone, Luciano Potena, Alberto Foà, Andreas Zuckermann

8. Donor Organ Harvesting and Preservation
Jonida Bejko, Giuseppe Feltrin, Annalisa Angelini, Gino Gerosa

9. Perioperative Myocardial Damage to the Graft
Annalisa Angelini, Marny Fedrigo

Part IV. Post-cardiac Transplantation: The Multiple Faces of Rejection

10. Graft Failure/Dysfunction: Clinical Issues and Role of Endomyocardial Biopsy
Luciano Potena, Valentina Manfredini, Ornella Leone

11. Clinical Management of Transplant Recipients
Marco Masetti, Francesco Grigioni

12. Practical Immunology for Pathologists
John D. Smith, Marlene L. Rose

13. Pathology of Acute Cellular Rejection
Desley A. H. Neil, Alexandra J. Rice

14. Pathology of Antibody-Mediated Rejection
Samuel Rotman, Dylan V. Miller, Claire Toquet, Gerald J. Berry

15. “Mixed” Rejection in Heart Transplantation
Dylan V. Miller, Abdallah G. Kfoury

16. Pathological Non-rejection Findings in the Endomyocardial Biopsy
Helen Doran, Desley A. H. Neil

17. Noninvasive Tools for Monitoring Acute Cardiac Allograft Rejection: State of the Art
Marie-Claude Parent, Brian A. Clarke, Kiran K. Khush

18. Cardiac Allograft Vasculopathy
Marny Fedrigo, Jorge Pombo Otero, Francesco Tona, Carlo Dal Lin, Marisa Crespo Leiro, Patrick Bruneval

Part V. Post-cardiac Transplantation: Complications Other than Rejection

19. Infections
David Lebeaux, Julien Coussement, Sylvain Poiree, Olivier Lortholary

20. Malignancies After Heart Transplantation
Valentina Agostini, Heike Goebel, Luciano Potena, Gerald J. Berry, Ornella Leone

21. Chronic Kidney Disease After Heart Transplantation: Risk Factors, Clinics, and Histopathology
Gaia Magnani, Marialuisa Valente, Francesco Marchini

Part VI. Special Issues in Cardiac Transplantation

22. Pathology of Pediatric Heart Transplantation
Jean-Paul Duong Huyen, Franck Iserin, Claire Toquet

23. Combined Heart Transplants
Martin Goddard

24. The Autopsy in Heart Transplantation
Annalisa Angelini, Marny Fedrigo, Margaret Burke

25. Examination of Native Hearts with Implantable Mechanical Circulatory Support Systems
Klaus Aumayr, Katharina Wassilew

Keywords: Medicine & Public Health, Pathology, Cardiology, Cardiac Surgery, Immunology